Evidence map›Paper›PMID 31323765›Full record

ArticleInternational journal of environmental research and public health2019

Proposal of an Adapted Physical Activity Exercise Protocol for Women with Osteoporosis-Related Vertebral Fractures: A Pilot Study to Evaluate Feasibility, Safety, and Effectiveness.

Sofia Marini, Erica Leoni, Alessandra Raggi, Tiziana Sanna, Nazzarena Malavolta, Buffa Angela, Pasqualino Maietta Latessa, Laura Dallolio

Abstract readControlled Clinical Trial
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Conservative treatments for non-surgically managed osteoporotic vertebral compression fractures: a network meta-analysis of long-term pain and quality of life.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Effectiveness and safety of physical exercise and health education for the management of osteoporotic vertebral fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  6. Falls efficacy and directional postural sway responses during the sensory organization test in adults with nonspecific chronic low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sofia MariniDepartment of Life Quality Studies, University of Bologna, Campus of Rimini, Corso d'Augusto 237, 47921 Rimini, Italy.ORCID 0000-0002-7025-4271
Erica LeoniUnit of Hygiene, Public Health and Medical Statistics, Department of Biomedical and Neuromotor Sciences, University of Bologna, via San Giacomo 12, 40126 Bologna, Italy.ORCID 0000-0002-4002-9153
Alessandra RaggiSchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, University of Bologna, via San Giacomo 12, 40126 Bologna, Italy.
Tiziana SannaSchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, University of Bologna, via San Giacomo 12, 40126 Bologna, Italy.
Nazzarena MalavoltaSant'Orsola-Malpighi Hospital of Bologna, Unit of Internal Medicine, Section of Rheumatology, via Pietro Albertoni, 15, 40138 Bologna, Italy.
Buffa AngelaSant'Orsola-Malpighi Hospital of Bologna, Unit of Internal Medicine, Section of Rheumatology, via Pietro Albertoni, 15, 40138 Bologna, Italy.
Pasqualino Maietta LatessaDepartment of Life Quality Studies, University of Bologna, Campus of Rimini, Corso d'Augusto 237, 47921 Rimini, Italy.
Laura DallolioUnit of Hygiene, Public Health and Medical Statistics, Department of Biomedical and Neuromotor Sciences, University of Bologna, via San Giacomo 12, 40126 Bologna, Italy. laura.dallolio@unibo.it.ORCID 0000-0001-7555-9659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A quasi-experimental pilot study was performed to determine the feasibility and safety of an Adapted Physical Activity (APA) protocol and its effect on health-related quality of life (HRQOL), fear of falling, pain, and physical performance in women with osteoporosis-related vertebral fractures. Forty-four post-menopausal women (mean age: 67.6 ± 4.6) with osteoporotic vertebral fractures were assigned to an exercise group (APA group = 26) who attended a six-month exercise protocol that included postural and muscular reinforcement exercises, and a control group (CG = 18) who was asked to maintain their current lifestyle. At baseline and six months after baseline, HRQOL was measured as primary outcome by the Assessment of Health Related Quality of Life in Osteoporosis (ECOS-16) questionnaire. Secondary outcomes were fear of falling (Fall Efficacy Scale International, FES-I), lumbar back pain (Visual Analogue Scale-VAS), functional exercise capacity (Six Minutes Walking Test-6MWT, Borg scale), balance and gait (Tinetti Scale), and flexibility of the column (Chair Sit-and-Reach). The effects of the intervention were analyzed by comparison within groups and between groups. Effect sizes (ES) were calculated using Cohen's d. All the outcomes significantly improved in the APA group, while they remained unchanged in the CG. After adjustment for unbalanced variables, the comparison between groups showed significant effects of the intervention for ECOS-16-score, functional exercise capacity, balance, and gait. The exercise program had big effect sizes on HRQOL (ES = 1.204), fear of falling (ES = 1.007), balance (ES = 0.871), and functional exercise capacity (ES = 1.390). Good adherence (75.8%) and no injuries were observed. Due to its feasibility, safety, and effectiveness, the proposed exercise protocol can be adopted in APA programs addressed to patients with osteoporosis-related vertebral fractures.

Indexed as

Accidental FallsAgedExerciseExercise TherapyExercise ToleranceFearFeasibility StudiesFemaleFractures, BoneGaitHumansLow Back PainMiddle AgedOsteoporosisPilot ProjectsPostural Balanceadapted physical activityfear of fallinghealth-related quality of lifeosteoporosis-related vertebral fracturesphysical performance

Identifiers

PMID31323765
PMCPMC6679098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.