ArticleThe Annals of thoracic surgery2019
A Prolonged Air Leak Score for Lung Cancer Resection: An Analysis of The Society of Thoracic Surgeons General Thoracic Surgery Database.
Article in The Annals of thoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04954625 (Prolonged Air Leak), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prolonged Air Leak (PAL) Autologous Blood Patch Intervention Trial
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Prediction models for prolonged air leak after pulmonary surgery: a systematic review and critical appraisal.Frontiers in oncology · 2026Pooled it
- Autologous mesenchymal stromal cells embedded with Tissucol DuoStem cell research & therapy · 2023Trial
- Neoveil versus TachoSil in the treatment of pulmonary air leak following open lung surgery: a prospective randomized trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2022Trial
- Construction and validation of a nomogram for predicting prolonged air leak after minimally invasive pulmonary resection.World journal of surgical oncology · 2022Trial
- Intraoperative Volume Decay Measured Through Mechanical Ventilation as a Predictor of Prolonged Postoperative Air Leak After Uniportal Video-Assisted Thoracic Surgery Lung Resection.Journal of personalized medicine · 2026Article
- Robotic vs. bedside staplers in robotic lung resection: a real-world cohort study.Journal of robotic surgery · 2026Article
- Endoluminal approaches to postoperative air leaks.Journal of thoracic disease · 2026Review
- Article
- Can Artificial Intelligence Interpret Pulmonary Function Tests and Predict Prolonged Air Leaks After Lung Resection.Cancers · 2026Article
- RoboticJournal of thoracic disease · 2026Article
- Efficacy of bioabsorbable staple line reinforcement in reducing air leakage following pulmonary resection: a cadaveric study.Journal of thoracic disease · 2026Article
- Article
- NODRAIN study protocol: a non-interventional, prospective study for evaluating the effectiveness of intraoperative ventilation for the prediction of postoperative air leak in major pulmonary resections by conventional or robotic thoracoscopy.Journal of thoracic disease · 2026Article
- The importance of an inspiratory hold and a prolonged inspiratory ramp for the detection of bronchopleural leaks in anJournal of thoracic disease · 2025Article
- Implantation of polyglycolic acid mesh over lung resection staple lines to prevent air leaks.JTCVS techniques · 2025Article
- Clinical impact of surgical approaches on early-phase postoperative air leakage.Scientific reports · 2025Observational
- Impact of pre-operative inflammatory markers on overall and disease-free survival of octogenarian patients undergoing video-assisted thoracoscopic lobectomy for early-stage lung cancer: a multicenter study.Journal of thoracic disease · 2025Article
- Routine conventional leak test is not required for robotic major pulmonary resections.General thoracic and cardiovascular surgery · 2025Article
- Phrenic nerve infiltration: A good practice to combine pulmonary expansion and pain control in patients with high risk of prolonged air leak.JTCVS open · 2025Article
- Pneumothorax After VATS for Pleural Empyema in Pediatric Patients.Children (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe objective of this study was to create a simple preoperative tool to assess the risk of prolonged air leak (PAL) using The Society of Thoracic Surgeons General Thoracic Surgery Database (STS GTSD).
methodsThe STS GTSD was queried for patients who underwent elective lung cancer resection between 2009 and 2016. Exclusion criteria included pneumonectomy, sleeve lobectomy, chest wall resection, bilateral procedures, and patients with incomplete data sets. The primary outcome was PAL exceeding 5 days. Multivariable logistic regression was used to identify risk factors for a PAL. Model coefficients were used to generate a PAL score (PALS). The approach was cross-validated in 100 replications of a training set consisting of two-thirds of the cohort that was randomly selected and a validation set of remaining patients.
resultsA total of 52,198 patients from the STS GTSD met inclusion criteria, with an overall rate of PAL of 10.4% (n = 5453). Final variables incorporated into the PALS included body mass index of 25 kg/m
conclusionsThe PALS is a simple preoperative clinical tool that can reliably risk-stratify patients for PAL who are undergoing lung cancer resection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.