Evidence map›Paper›PMID 31322429›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2019

Transcriptomic evidence that cortisol alters perinatal epicardial adipose tissue maturation.

Elaine M Richards, Emily McElhaney, Katelyn Zeringue, Serene Joseph, Maureen Keller-Wood

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Maternal hypercortisolemia alters placental metabolism: a multiomics view.American journal of physiology. Endocrinology and metabolism · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elaine M RichardsDepartment of Pharmacodynamics, University of Florida, Gainesville, Florida.
Emily McElhaneyDepartment of Pharmacodynamics, University of Florida, Gainesville, Florida.
Katelyn ZeringueDepartment of Pharmacodynamics, University of Florida, Gainesville, Florida.
Serene JosephDepartment of Pharmacodynamics, University of Florida, Gainesville, Florida.
Maureen Keller-WoodDepartment of Pharmacodynamics, University of Florida, Gainesville, Florida.
University of Florida · US

Funding

Effects of maternal cortisol on fetal and neonatal growth and metabolismR01HD057871 · NICHD · UNIVERSITY OF FLORIDA · PI KELLER-WOOD, MAUREEN · 2009 to 2013
$1.5M
NICHD NIH HHS R01 HD057871
6 · The paper itself

Abstract

Cortisol administration during late gestation in ewes, modeling maternal stress, resulted in transcriptomic changes suggesting altered maturation and metabolic changes to the offspring heart. This study investigates the effects of cortisol on epicardial adipose tissue (EAT), a visceral fat pad associated with adverse cardiovascular conditions in adults. Pregnant ewes were treated with either 1 mg·kg

Indexed as

AdipogenesisAdipose TissueAdipose Tissue, BrownAdipose Tissue, WhiteAnimalsAnimals, NewbornFemaleGene ExpressionHeartHydrocortisoneLipid PeroxidationMyocardiumPericardiumPregnancySheep, DomesticTranscriptomeHydrocortisoneadiposegene expressionheartpregnancystress

Identifiers

PMID31322429
PMCPMC6842920
OpenAlexW2964032032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.