Evidence map›Paper›PMID 31322412›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2019

Effects of multiple cycles of weight loss and regain on the body weight regulatory system in rats.

Jennifer L Rosenbaum, R Scott Frayo, Susan J Melhorn, David E Cummings, Ellen A Schur

Abstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer L RosenbaumDepartment of Endocrinology, Metabolism and Nutrition, University of Washington, Seattle, Washington.ORCID 0000-0002-4088-9022
R Scott FrayoLaboratory of Renal Pathology, University of Washington, Seattle, Washington.
Susan J MelhornDepartment of Internal Medicine, University of Washington, Seattle, Washington.
David E CummingsDepartment of Endocrinology, Metabolism and Nutrition, Seattle Veterans Administration Hospital, Seattle, Washington.
Ellen A SchurDepartment of Internal Medicine, University of Washington, Seattle, Washington.

Funding

PILOT STUDY--CLINICAL NUTRITION RESEARCHP30DK035816 · NIDDK · UNIVERSITY OF WASHINGTON · PI GREGORY J MORTON · 1986 to 2026
$30.4M
Nutrition, Obesity and Atherosclerosis Training ProgramT32HL007028 · NHLBI · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1985 to 2026
$6.4M
A twin study of obesity pathogenesis using fMRIR01DK089036 · NIDDK · UNIVERSITY OF WASHINGTON · PI SCHUR, ELLEN A · 2011 to 2022
$6.2M
Brain systems and behaviors underlying response to obesity treatment in childrenR01DK098466 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI ROTH, CHRISTIAN LUDWIG · 2014 to 2023
$5.6M
Fostering patient-oriented research in cardiometabolic disease pathogenesis and preventionK24HL144917 · NHLBI · UNIVERSITY OF WASHINGTON · PI Ellen A Schur · 2019 to 2026
$965k
An interdisciplinary study of eating behavior in twinsK23DK070826 · NIDDK · UNIVERSITY OF WASHINGTON · PI SCHUR, ELLEN A · 2005 to 2009
$626k
NHLBI NIH HHS K24 HL144917NHLBI NIH HHS T32 HL007028NIDDK NIH HHS K23 DK070826NIDDK NIH HHS P30 DK035816NIDDK NIH HHS R01 DK089036NIDDK NIH HHS R01 DK098466
6 · The paper itself

Abstract

We studied the effects of multiple cycles of weight loss and regain on the defended body weight in rats. Thirty-six male Wistar rats were divided into three weight-matched groups: weight cyclers (

Indexed as

AdiposityAnimalsBody CompositionBody WeightCaloric RestrictionDiet, ReducingGhrelinGlucose Tolerance TestInsulinLeptinMaleRatsRats, WistarWeight LossGhrelinInsulinLeptinghrelinweight cyclingweight maintenance

Identifiers

PMID31322412
PMCPMC6879866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.