Evidence map›Paper›PMID 31322113›Full record

ArticleHealthcare policy = Politiques de sante2019

Policies for Deprescribing: An International Scan of Intended and Unintended Outcomes of Limiting Sedative-Hypnotic Use in Community-Dwelling Older Adults.

James Shaw, Andrea L Murphy, Justin P Turner, David M Gardner, James L Silvius, Zachary Bouck, Dara Gordon, Cara Tannenbaum

Open access · bronzeAbstract read
In one paragraph

Article in Healthcare policy = Politiques de sante, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

James ShawAssistant Professor, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON.
Andrea L MurphyAssociate Professor, College of Pharmacy, Dalhousie University, Halifax, NS.
Justin P TurnerGraduate Student, Centre de Recherche Institut Universitaire de Gériatrie de Montréal, Montreal, QC.
David M GardnerProfessor, Department of Psychiatry, Dalhousie University, Halifax, NS.
James L SilviusCo-Director, Canadian Deprescribing Network; Associate Professor, Department of Medicine, University of Calgary, Calgary, AB.
Zachary BouckBiostatistician, Women's College Hospital Institute for Health System Solutions and Virtual Care, Toronto, ON.
Dara GordonResearch Coordinator, Women's College Hospital Institute for Health System Solutions and Virtual Care, Toronto, ON.
Cara TannenbaumCo-Director, Canadian Deprescribing Network; Professor, Faculties of Medicine and Pharmacy Université de Montréal, Montreal, QC.
Dalhousie University · CA

Funding

CIHR 201410PHE-PHE-337814-96399
6 · The paper itself

Abstract

Policies have been put in place internationally to reduce the overuse of certain medications that have a high risk of harm, such as sedative-hypnotic drugs for insomnia or opioids for chronic non-cancer pain. We explore and compare the outcomes of policies aimed at deprescribing sedative-hypnotic medication in community-dwelling older adults. Prescription monitoring policies led to the highest rate of discontinuation but triggered inappropriate substitutions. Financial deterrents through insurance scheme delistings increased patient out-of-pocket spending and had minimal impact. Pay-for-performance incentives to prescribers proved ineffective. Rescheduling alprazolam to a controlled substance raised the street drug price of the drug and shifted use to other benzodiazepines, causing similar rates of overdose deaths. Driving safety policies and jurisdiction-wide educational campaigns promoting non-drug alternatives appear most promising for achieving intended outcomes and avoiding unintended harms. Sustainable change should be supported with direct-to-patient education and improved access to non-drug therapy, with an emphasis on evaluating both intended and unintended consequences of any deprescribing-oriented policy.

Indexed as

DeprescriptionsHealth PolicyAgedAged, 80 and overCanadaChronic PainDrug PrescriptionsFemaleHumansHypnotics and SedativesIndependent LivingMaleMiddle AgedHypnotics and Sedatives

Identifiers

PMID31322113
PMCPMC7008681
OpenAlexW2958476695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.