Evidence map›Paper›PMID 31322018›Full record

ReviewExpert review of clinical immunology2019

Overall and comparative safety of biologic and immunosuppressive therapy in inflammatory bowel diseases.

Ariela Holmer, Siddharth Singh

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Expert review of clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Guideline
  4. Article
  5. Article
  6. Article
  7. Comparative Safety of Janus Kinase Inhibitors vs Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Diseases.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  8. Review
  9. Infliximab asFrontiers in gastroenterology (Lausanne, Switzerland) · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Impact of Treatment Response on Risk of Serious Infections in Patients With Crohn's Disease: Secondary Analysis of the PYRAMID Registry.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ariela HolmerDivision of Gastroenterology, University of California San Diego , La Jolla , CA , USA.
Siddharth SinghDivision of Gastroenterology, University of California San Diego , La Jolla , CA , USA.
University of California, San Diego · US

Funding

Comparative Risks and Benefits of Pharmacological Therapies for Older Patients with Inflammatory Bowel DiseasesK23DK117058 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SINGH, SIDDHARTH · 2018 to 2022
$971k
NIDDK NIH HHS K23 DK117058
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdalimumabAntibodies, MonoclonalBiological ProductsCertolizumab PegolCrohn DiseaseHumansImmunosuppressive AgentsInflammatory Bowel DiseasesInfliximabTumor Necrosis Factor-alphaAdalimumabAntibodies, MonoclonalBiological ProductsCertolizumab PegolgolimumabImmunosuppressive AgentsInfliximabTumor Necrosis Factor-alphaCancerCrohn’s diseaseimmunosuppressioninfectionlymphomaulcerative colitis

Identifiers

PMID31322018
PMCPMC6813772
OpenAlexW2964085910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.