Evidence map›Paper›PMID 31321911›Full record

ArticleJournal of the International AIDS Society2019

Integrating PrEP into HIV care clinics could improve partner testing services and reinforce mutual support among couples: provider views from a PrEP implementation project in Kenya.

Josephine B Odoyo, Jennifer F Morton, Kenneth Ngure, Gabrielle O'Malley, Kenneth K Mugwanya, Elizabeth Irungu, Merceline Awuor, Annabell Dolla, Fernandos Ongolly, Elizabeth A Bukusi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Josephine B OdoyoKenya Medical Research Institute, Center for Microbiology Research, Nairobi, Kenya.
Jennifer F MortonDepartment of Global Health, University of Washington, Seattle, WA, USA.
Kenneth NgureDepartment of Global Health, University of Washington, Seattle, WA, USA.
Gabrielle O'MalleyDepartment of Global Health, University of Washington, Seattle, WA, USA.
Kenneth K MugwanyaDepartment of Global Health, University of Washington, Seattle, WA, USA.
Elizabeth IrunguDepartment of Global Health, University of Washington, Seattle, WA, USA.
Merceline AwuorKenya Medical Research Institute, Center for Microbiology Research, Nairobi, Kenya.
Annabell DollaKenya Medical Research Institute, Center for Microbiology Research, Nairobi, Kenya.
Fernandos OngollyKenya Medical Research Institute, Center for Clinical Research, Nairobi, Kenya.
Elizabeth A BukusiKenya Medical Research Institute, Center for Microbiology Research, Nairobi, Kenya.
Nelly R MugoDepartment of Global Health, University of Washington, Seattle, WA, USA.
Jared M BaetenDepartment of Global Health, University of Washington, Seattle, WA, USA.
Partners Scale-Up Project Team
University of Washington · USKenya Medical Research Institute · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Optimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1M
Bill & Melinda Gates Foundation OPP1056051NIAID NIH HHS P30 AI027757NIH HHS R01 MH095507NIMH NIH HHS R01 MH095507
6 · The paper itself

Abstract

introductionPartner notification services (PNS) increase the HIV status knowledge and linkage to care and treatment. However, it is unclear if PNS can facilitate linkage of HIV-negative partners to prevention services such as pre-exposure prophylaxis (PrEP). Using qualitative methods, we explored provider perspective regarding the interaction of PrEP availability, PNS and antiretroviral treatment (ART) outcomes within a project integrating PrEP services into HIV care clinics in eight counties in western and central Kenya.

methodsFrom May 2017 to August 2018, data on integrated PrEP service delivery including its interaction with PNS were collected through 71 key informant in-depth interviews with healthcare providers and 24 standardized technical assistance reports summarizing implementation at the participating clinics. Thus, the perspective was from that of providers; analyses focused on emergent themes relating PNS to PrEP and ART services.

resultsProviders found that PrEP integration provided an additional concrete prevention option for HIV-negative partners and created a motivation to offer PNS to persons living with HIV. PrEP availability also seemed to operate as an incentive for those living with HIV to participate in PNS, which in turn enhanced identification of potential PrEP clients and created an environment for discussing HIV transmission risk. Providers commented that initiating HIV-negative partners on PrEP enhanced mutual monitoring of health outcomes, including improved adherence to ART by partners living with HIV. Clinics noted prioritizing people living with HIV with detectable viral loads for PNS in order to identify HIV-negative partners who would benefit most from PrEP. Providers felt motivated by the apparent synergistic interaction of PNS, PrEP and ART.

conclusionsProviders felt that the integration of PrEP into HIV care clinics stimulated the provision of PNS, and PNS was used to improve the identification of potential PrEP clients. The integrated combination of PNS, PrEP and ART is synergistic and should be promoted in HIV clinics.

Indexed as

Contact TracingPre-Exposure ProphylaxisSexual PartnersAdultAnti-HIV AgentsFemaleHealth PersonnelHIV InfectionsHumansKenyaMaleTreatment OutcomeViral LoadYoung AdultAnti-HIV AgentsARTdisclosureHIVHIV care continuumpartner notification servicesPrEP

Identifiers

PMID31321911
PMCPMC6639665
OpenAlexW2964219977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.