Trial reportJournal of the International AIDS Society2019
Index participant characteristics and HIV assisted partner services efficacy in Kenya: results of a cluster randomized trial.
Trial report in Journal of the International AIDS Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- A Systematic Review of HIV Testing Implementation Strategies in Sub-Saharan African Countries.AIDS and behavior · 2022Pooled it
- Index participant characteristics and HIV assisted partner services efficacy in Kenya: results of a cluster randomized trial.Journal of the International AIDS Society · 2019Trial
- Assisted partner notification as a strategy to enhance Pre-Exposure Prophylaxis (PrEP) screening and uptake - results from a prospective cohort study in Lilongwe, Malawi.BMC health services research · 2025Article
- The Magnitude and Associated Factors of Early Index Case Testing Among Adult HIV Index Cases at Debre Markos Town High Load Health Facilities 2023.AIDS research and treatment · 2025Article
- Innovations in Providing HIV Index Testing Services: A Retrospective Evaluation of Partner Elicitation Models in Southern Nigeria.Global health, science and practice · 2024Article
- Effectiveness and safety of community-led assisted partner service among HIV-diagnosed men who have sex with men: a multicentre, randomized controlled trial in China.The Lancet regional health. Western Pacific · 2023Article
- Profile of partners who completed HIV testing and received a new HIV diagnosis in Ukraine's HIV index testing program: a retrospective cohort study to inform program improvement.BMC infectious diseases · 2023Observational
- Implementation process and challenges of index testing in Côte d'Ivoire from healthcare workers' perspectives.PloS one · 2023Article
- "I feel good because I have saved their lives": Acceptability of assisted partner services among female index clients and male sexual partners in Kenya.PLOS global public health · 2023Article
- Facilitators and barriers to status disclosure and partner testing of women living with HIV in Indonesia: a mixed methods study.Sexual and reproductive health matters · 2022Article
- Using Assisted Partner Services for HIV Testing and the Treatment of Males and Their Female Sexual Partners: Protocol for an Implementation Science Study.JMIR research protocols · 2021Article
- Index and targeted community-based testing to optimize HIV case finding and ART linkage among men in Zambia.Journal of the International AIDS Society · 2020Article
- The power of partners: positively engaging networks of people with HIV in testing, treatment and prevention.Journal of the International AIDS Society · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
introductionWe have previously demonstrated that assisted partner services (aPS) increases HIV testing and case finding among partners of persons living with HIV (PLHIV) in a cluster randomized trial in Kenya. However, the efficacy of aPS may vary across populations. In this analysis, we explore differences in aPS efficacy by characteristics of index participants.
methodsEighteen HIV testing sites were randomized to immediate versus 6-week delayed aPS. Participants were PLHIV (or index participants) and their sexual partners. Partners of index participants were contacted for HIV testing and linked to care if HIV positive. Primary outcomes were the number of partners per index participant who: 1) tested for HIV, 2) tested HIV positive and 3) enrolled in HIV care. We used generalized estimating equations to assess differences in aPS efficacy by region, testing location, gender, age and knowledge of HIV status.
resultsFrom 2013 to 2015, the study enrolled 1119 index participants, 625 of whom were in the immediate group. These index participants named 1286 sexual partners. Immediate aPS was more efficacious than delayed aPS in promoting HIV testing among partners in high compared to low HIV prevalence regions (Nyanza incidence rate ratio (IRR) 7.2; 95% confidence interval (CI) 5.4, 9.6 vs. Nairobi/Central IRR 3.4 95% CI 2.3, 4.8). Higher rates of partner HIV testing were also observed for index participants in rural/peri-urban compared to urban sites (IRR 6.6; 95% CI 4.5, 9.6 vs. IRR 3.5 95% CI 2.5, 5.0 respectively), for female versus male index participants (IRR 5.8 95% CI 4.2, 7.9 vs. IRR 3.7; 95% CI 2.4, 5.8 respectively) and for newly diagnosed versus known HIV-positive index participants (IRR 6.0 95% CI 4.2, 8.7 vs. IRR 3.3; 95% CI 2.0, 7.7 respectively). Providing aPS to female versus male index participants also had a significantly higher HIV case finding rate (IRR 9.1; 95% CI 4.0, 20.9 vs. IRR 3.2 95% CI 1.7, 6.0 respectively.)
conclusionsWhile it is known that aPS promotes increases in HIV testing and case finding, this is the first study to demonstrate significant differences in aPS efficacy across characteristics of the index participant. Understanding these differences and their drivers will be critical as aPS is brought to scale in order to ensure all PLHIV have access to these services.
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