ArticleJournal of endocrinological investigation2020
Laser photocoagulation therapy for thyroid nodules: long-term outcome and predictors of efficacy.
Article in Journal of endocrinological investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The long-term effects of thermal ablation for benign thyroid nodules: a systematic review and meta-analysis.European radiology · 2025Pooled it
- Long-term clinical outcomes of thermal ablation for benign thyroid nodules and unresolved issues: a comprehensive systematic review.La Radiologia medica · 2025Pooled it
- Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.Endocrinology and metabolism (Seoul, Korea) · 2020Pooled it
- Evaluating microwave ablation for treating large benign thyroid nodules.Gland surgery · 2026Article
- The association between volume reduction ratio and time after ultrasound-guided microwave ablation for benign thyroid nodules of different compositions.Quantitative imaging in medicine and surgery · 2025Article
- Predicting the efficacy of microwave ablation of benign thyroid nodules from ultrasound images using deep convolutional neural networks.BMC medical informatics and decision making · 2025Article
- The safety and efficacy of radiofrequency ablation in benign pediatric thyroid disease in the US: An initial case series.Laryngoscope investigative otolaryngology · 2024Article
- Efficacy on radiofrequency ablation according to the types of benign thyroid nodules.Scientific reports · 2021Article
- Long-Term Outcomes of Thermal Ablation for Benign Thyroid Nodules: The Issue of Regrowth.International journal of endocrinology · 2021Review
- Ultrasound-Guided Thermal Ablation of Thyroid Nodules: Technicalities Progress and Clinical Applications, Especially in Malignant Thyroid Nodules.Frontiers in oncology · 2021Review
- Long-Term Follow-Up of Single-Fiber Multiple Low-Intensity Energy Laser Ablation Technique of Benign Thyroid Nodules.Frontiers in oncology · 2021Article
- Machine Learning Prediction of Radiofrequency Thermal Ablation Efficacy: A New Option to Optimize Thyroid Nodule Selection.European thyroid journal · 2020Article
- Twelve-Month Volume Reduction Ratio Predicts Regrowth and Time to Regrowth in Thyroid Nodules Submitted to Laser Ablation: A 5-Year Follow-Up Retrospective Study.Korean journal of radiology · 2020Article
- Radiofrequency ablation of functioning and non-functioning thyroid nodules: a single institution 12-month survey.Journal of endocrinological investigation · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the present study was to retrospectively evaluate the efficacy of interstitial laser photocoagulation (ILP) ablation of thyroid nodules during a 6-year follow-up period and to identify possible predictors of the final outcome.
methodsForty-three outpatients (38 women) were assigned to ILP therapy. The study group included euthyroid patients with benign thyroid nodules. Thyroid size, nodule volume and features, and autoimmune test were collected at baseline. Patients underwent US control after the ILP procedure and 1 month, 6 months, 12 months later and then annually.
resultsDuring the follow-up, two distinct groups of patients emerged: the responders (N = 33) and the non-responder (N = 10) ones to ILP. In the responder group, the nodule volume significantly decreased during the follow-up, but a trend toward a slight increase in nodule volume was recorded up to the end of follow-up. No significant decrease in nodule volume was observed in the non-responder group. Neither baseline clinical nor demographic features were significantly different between responders and non-responders groups. In the whole group of patients, the energy delivered per mL of nodule tissue was significantly correlated with the percent volume decrease at the end of follow-up.
conclusionsInterstitial laser photocoagulation is a safe technique able to reduce byabout 50% the volume of benign thyroid nodules in the majority of treated patients. However, due to the great variability of results, an active follow-up is required. The only independent predictor of ILP outcome is the energy delivered per mL of nodule tissue.
Indexed as
Identifiers
31321758What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.