Evidence map›Paper›PMID 31321745›Full record

ReviewJournal of nephrology2019

Atrial fibrillation and chronic kidney disease conundrum: an update.

Laura Tapoi, Carina Ureche, Radu Sascau, Silvia Badarau, Adrian Covic

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Atrial fibrillation in advanced renal failure: are there alternative solutions to warfarin-dicumarol?European heart journal supplements : journal of the European Society of Cardiology · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Laura TapoiInstitute of Cardiovascular Disease "Prof. Dr. George I.M. Georgescu", Iasi, Romania.
Carina UrecheInstitute of Cardiovascular Disease "Prof. Dr. George I.M. Georgescu", Iasi, Romania. carina.ureche@yahoo.com.ORCID http://orcid.org/0000-0003-1495-5062
Radu SascauInstitute of Cardiovascular Disease "Prof. Dr. George I.M. Georgescu", Iasi, Romania.
Silvia Badarau"Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Adrian Covic"Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common cardiac arrhythmia and it is frequently encountered in chronic kidney disease (CKD) subjects. CKD patients are already at high risk for cardiovascular (CV) complications and the addition of AF further aggravates the prognosis. Data is missing regarding on how to best approach CKD patients with AF, due to lack of randomized controlled trials (RCTs). AF and CKD have a double edged-sword relationship. On one hand, there are kidney-specific mechanisms which can alter cardiac structure and predispose to AF, and on the other hand the development of AF itself can accelerate the progression of CKD. Furthermore, the synergistic effect of these two entities raises serious issues concerning the balance between bleeding and thrombotic risk. Anticoagulant treatment can be challenging, especially in end stage renal disease (ESRD), where the net clinical benefit is still unclear. The decision of rate vs. rhythm control lies mostly on general consensus, rather than on RCTs. The purpose of this review is to reinforce the symbiotic relationship between AF and CKD, to briefly summarize the current state of the therapeutic approach in this particular population and to highlight novel potential therapeutic strategies.

Indexed as

AnticoagulantsAtrial FibrillationHumansRenal Insufficiency, ChronicThromboembolismAnticoagulantsAtrial fibrillationChronic kidney diseaseHemodialysisOral anticoagulant therapy

Identifiers

PMID31321745
OpenAlexW2963305747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.