Evidence map›Paper›PMID 31321706›Full record

SynthesisThe patient2019

Patient Preferences for Breast Cancer Treatment Interventions: A Systematic Review of Discrete Choice Experiments.

Renata Leborato Guerra, Luciana Castaneda, Rita de Cássia Ribeiro de Albuquerque, Camila Belo Tavares Ferreira, Flávia de Miranda Corrêa, Ricardo Ribeiro Alves Fernandes, Liz Maria de Almeida

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The patient, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  4. Willingness-to-pay for cancer treatment and outcome: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Renata Leborato GuerraHealth Technology Assessment Unit of the Brazilian National Institute of Cancer, Rua Marquês de Pombal 125, 7º andar, Centro, Rio de Janeiro, RJ, CEP: 20.230-240, Brazil. renataleborato@gmail.com.ORCID 0000-0002-7507-6435
Luciana CastanedaHealth Technology Assessment Unit of the Brazilian National Institute of Cancer, Rua Marquês de Pombal 125, 7º andar, Centro, Rio de Janeiro, RJ, CEP: 20.230-240, Brazil.
Rita de Cássia Ribeiro de AlbuquerqueHealth Technology Assessment Unit of the Brazilian National Institute of Cancer, Rua Marquês de Pombal 125, 7º andar, Centro, Rio de Janeiro, RJ, CEP: 20.230-240, Brazil.
Camila Belo Tavares FerreiraIntegrated Library System, Teaching Coordination of the Brazilian National Cancer Institute, Rio de Janeiro, Brazil.
Flávia de Miranda CorrêaHealth Technology Assessment Unit of the Brazilian National Institute of Cancer, Rua Marquês de Pombal 125, 7º andar, Centro, Rio de Janeiro, RJ, CEP: 20.230-240, Brazil.
Ricardo Ribeiro Alves FernandesHealth Technology Assessment Unit of the Brazilian National Institute of Cancer, Rua Marquês de Pombal 125, 7º andar, Centro, Rio de Janeiro, RJ, CEP: 20.230-240, Brazil.
Liz Maria de AlmeidaPopulational Research Division of the Brazilian National Institute of Cancer, Rio de Janeiro, Brazil.
Instituto Nacional de Câncer - INCA · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUnderstanding how patients value different characteristics of an intervention and make trade-offs in a therapy choice context with potential benefit and possible harm may result in decisions for which a better reflected value is delivered. This systematic review summarizes patient preferences for breast cancer treatments elicited by discrete choice experiments (DCE). METHODOLOGY: The electronic databases MEDLINE (PubMed), Scopus, PsycINFO, CINAHL, LILACS, and Web of Science were last searched on May 9, 2019 without restrictions regarding language and time of publication. Original studies reporting patient preferences related to breast cancer treatment (surgery, radiotherapy, endocrine therapy, chemotherapy or palliative care) elicited by DCE were eligible. A narrative synthesis of the relative importance and trade-offs of the treatment attributes of each study was reported.

resultsFive studies conducted in Japan, Thailand, USA and the Netherlands with 146-298 participants evaluated preferences regarding chemotherapy regimens for advanced/metastatic disease, and breast reconstruction after mastectomy. The attributes with major relative effects on preferences were greater survival, better aesthetic result of the surgery, and lower side effects and complication rates. Patients would trade a better aesthetic result to minimize complication rates, and, in advanced disease, the willingness to pay was greater for gains in survival and to avoid some severe adverse events.

conclusionDespite the relative lack of evidence in this specific context, our review shows that breast cancer patients naturally value greater benefit and, in scenarios of advanced and metastatic disease, are willing to face risks of some side effects for gains in survival.

Indexed as

Choice BehaviorPatient PreferenceBreast NeoplasmsFemaleHumansMiddle Aged

Identifiers

PMID31321706
OpenAlexW2964088882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.