Evidence map›Paper›PMID 31321619›Full record

ArticleJapanese journal of radiology2019

Liver imaging reporting and data system (LI-RADS) v2018: comparison between computed tomography and gadoxetic acid-enhanced magnetic resonance imaging.

Sei Nakao, Masahiro Tanabe, Munemasa Okada, Matakazu Furukawa, Etsushi Iida, Keisuke Miyoshi, Naofumi Matsunaga, Katsuyoshi Ito

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Japanese journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Trial
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sei NakaoDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.
Masahiro TanabeDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan. itokatsu@yamaguchi-u.ac.jp.
Munemasa OkadaDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.
Matakazu FurukawaDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.
Etsushi IidaDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.
Keisuke MiyoshiDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.
Naofumi MatsunagaDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.
Katsuyoshi ItoDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Yamaguchi, Japan.ORCID http://orcid.org/0000-0002-1483-0369

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the consistency of major hepatocellular carcinoma (HCC) features between CT and MRI based on Liver Imaging Reporting and Data System (LI-RADS) v2018 and to investigate the additional value on gadoxetic acid-enhanced MRI. MATERIALS AND

methodsPatients who underwent dynamic CT and gadoxetic acid-enhanced MRI within 1 month were investigated. Two radiologists evaluated the presence of major HCC features and categorized observations using LI-RADS v2018 algorithm. In addition, each observation was recorded as hyper-, iso-, or hypo-intensity on hepatobiliary-phase (HBP) images.

resultsSixty-one patients with 110 observations were identified. Among 88 observations classified as LR-3, 4 or 5, arterial phase hyper-enhancement and washout appearance showed higher frequencies on CT than on MRI (75.0% vs. 58.0%, P < 0.001, and 60.2% vs. 44.3%, P = 0.014, respectively). Of the 59 LR-3 observations categorized on MRI, 70.0% of observations with hypo-intensity on HBP images were HCCs, whereas 89.5% of observations with iso- or hyper-intensity on HBP images were non-HCCs (P < 0.001)

conclusionThe frequencies of arterial phase hyper-enhancement and washout appearances were higher on CT than on gadoxetic acid-enhanced MRI. For LR-3 observations, adding the hepatobiliary-phase hypo-intensity to major features improved the diagnostic performance of MRI in distinguishing HCCs from non-HCC lesions.

Indexed as

Gadolinium DTPARadiology Information SystemsAdultAgedAged, 80 and overAlgorithmsCarcinoma, HepatocellularContrast MediaFemaleHumansImage EnhancementLiverLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPACTGadoxetic acid-enhanced MRIHepatocellular carcinomaLiver imaging reporting and data system

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.