Evidence map›Paper›PMID 31321565›Full record

ReviewCurrent hypertension reports2019

Anxiety and Hypertension: Is There a Link? A Literature Review of the Comorbidity Relationship Between Anxiety and Hypertension.

Heather M Johnson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  4. Gender Differences in the Association Between Depression, Anxiety and Cardiovascular Mortality in Hypertensive Patients: A Cohort Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Heather M JohnsonDepartment of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine & Public Health, H4/512 CSC, MC 3248, 600 Highland Avenue, Madison, WI, 53792, USA. hm2@medicine.wisc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo review the most recent literature on the association between comorbid anxiety disorders and hypertension. RECENT

findingsRecent longitudinal and cross-sectional studies across geographic regions and age groups predominantly demonstrate a positive association between comorbid anxiety and prevalent or incident hypertension. Growing research on blood pressure variability and reduced baroreflex sensitivity in response to autonomic dysfunction provides a greater understanding of mechanistic relationships between anxiety and hypertension. Observational studies demonstrate that young adults are at a higher risk for developing incident hypertension after an anxiety diagnosis, supporting longer exposure to alterations in autonomic mechanisms. Confounding relationships of comorbid anxiety with depression likely contribute to prior conflicting results on the association between anxiety and hypertension. There is increasing evidence of a positive association between comorbid anxiety and hypertension. This contemporaneous review supports similar findings in historical studies and provides mechanistic hypotheses for larger, longitudinal studies.

Indexed as

AnxietyAnxiety DisordersComorbidityCross-Sectional StudiesHealth BehaviorHumansHypertensionYoung AdultAnxiety disorderAutonomic nervous systemComorbidityHealth behaviorHypertensionRisk factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.