Evidence map›Paper›PMID 31321447›Full record

ArticleExperimental brain research2019

Intracerebroventricular administration of histidine reduces kainic acid-induced convulsive seizures in mice.

Serdar Alpdogan, Felix Neumaier, Maxine Dibué-Adjei, Jürgen Hescheler, Toni Schneider

Abstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Serdar AlpdoganInstitute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Koeln, Germany.
Felix NeumaierInstitute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Koeln, Germany.
Maxine Dibué-AdjeiInstitute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Koeln, Germany.
Jürgen HeschelerInstitute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Koeln, Germany.
Toni SchneiderInstitute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Koeln, Germany. toni.schneider@uni-koeln.de.ORCID http://orcid.org/0000-0003-2816-2696
University of Cologne · DE

Funding

Deutsche Forschungsgemeinschaft Schn 387/21-1
6 · The paper itself

Abstract

Kainic acid (KA)-induced seizures and other experimental models of epilepsy have been proven to be instrumental in identifying novel targets that could be responsible for human icto- and epileptogenesis. We have previously shown that the ablation of pharmacoresistant voltage-gated Ca

Indexed as

AnimalsDisease Models, AnimalHippocampusHistidineIonsKainic AcidMice, Inbred C57BLSeizuresSignal TransductionHistidineIonsKainic AcidPharmacoresistant calcium channelPlastic cannulasR-typeTelemetryTrace metal cations

Identifiers

PMID31321447
OpenAlexW2963493413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.