Evidence map›Paper›PMID 31321427›Full record

Trial reportJournal of the American Medical Informatics Association : JAMIA2019

The effect of medication cost transparency alerts on prescriber behavior.

Craig B Monsen, Joshua M Liao, Barak Gaster, Kevin J Flynn, Thomas H Payne

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. A Surgeon's Field Guide to Value-Based Specialty Care.Laryngoscope investigative otolaryngology · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Canadian family physician Medecin de famille canadien · 2020
    Article
  15. Engaging physicians to prescribe more cost-effectively: Blueprint for change.Canadian family physician Medecin de famille canadien · 2020
    Article
  16. Article
  17. Need for innovation in electronic health record-based medication alerts.Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Craig B MonsenCenter for Analytics and Informatics, Atrius Health, Newton, Massachusetts, USA.
Joshua M LiaoDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Barak GasterDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Kevin J FlynnDepartment of Pharmacy Services, University of Washington, Seattle, Washington, USA.
Thomas H PayneDepartment of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to determine if medication cost transparency alerts provided at time of prescribing led ambulatory prescribers to reduce their use of low-value medications. MATERIALS AND

methodsProvider-level alerts were deployed to ambulatory practices of a single health system from February 2018 through April 2018. Practice sites included 58 primary care and 152 specialty care clinics totaling 1896 attending physicians, residents, and advanced practice nurses throughout western Washington. Prescribers in the randomly assigned intervention arm received a computerized alert whenever they ordered a medication among 4 high-cost medication classes. For each class, a lower cost, equally effective, and safe alternative was available. The primary outcome was the change in prescribing volume for each of the 4 selected medication classes during the 12-week intervention period relative to a prior 24-week baseline.

resultsA total of 15 456 prescriptions for high-cost medications were written during the baseline period including 7223 in the intervention arm and 8233 in the control arm. During the intervention period, a decrease in daily prescribing volume was noted for all high-cost medications including 33% for clobetasol propionate (p < .0001), 59% for doxycycline hyclate (p < .0001), 43% for fluoxetine tablets (p < .0001), and a non-significant 3% decrease for high-cost triptans (p = .65). Prescribing volume for the high-cost medications overall decreased by 32% (p < .0001).

conclusionMedication cost transparency alerts in an ambulatory setting lead to more cost-conscious prescribing. Future work is needed to predict which alerts will be most effective.

Indexed as

Practice Patterns, Physicians'Prescription FeesAmbulatory CareDrug Therapy, Computer-AssistedElectronic Health RecordsHealth ExpendituresHumansReminder Systemsalertsbehavioral nudgescost transparencydecision supportmedicationspragmatic trial

Identifiers

PMID31321427
PMCPMC7647180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.