Evidence map›Paper›PMID 31321376›Full record

ArticleCurrent developments in nutrition2019

Lutein across the Lifespan: From Childhood Cognitive Performance to the Aging Eye and Brain.

James M Stringham, Elizabeth J Johnson, B Randy Hammond

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06270680 (Efficacy of Carotenoids on Blood Biomarkers Following A Collision Sport Athletes), which is not on this map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06270680 early_phase1completednot on this mapstarted 2024, after this paper: background citation

Efficacy of Carotenoids on Blood Biomarkers Following A Collision Sport Athletes

TypeinterventionalSponsorPenn State UniversityRan2024 to 2024Enrolled31ConditionsHead Injury, CarotenoidsArmsVision Edge Pro, Placebo
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Pigments from pathogenic bacteria: a comprehensive update on recent advances.World journal of microbiology & biotechnology · 2024
    Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

James M StringhamVisual performance Laboratory, Duke Eye Center, Durham, NC, USA.ORCID 0000-0002-1476-1084
Elizabeth J JohnsonFriedman School of Nutrition, Tufts University, Boston, MA, USA.ORCID 0000-0002-8508-0032
B Randy HammondDepartment of Psychology, University of Georgia-Athens, Athens, GA, USA.
Tufts University · USUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lutein is a non-provitamin A dietary carotenoid found in dark green leafy vegetables, corn, eggs, and avocados. Among the carotenoids, lutein and its isomer, zeaxanthin, are the only 2 that cross the blood-retina barrier to form macular pigment in the retina. Lutein also preferentially accumulates in the human brain across multiple life stages. A variety of scientific evidence supports a role for lutein in visual as well as cognitive function across the lifespan. The purpose of this review is to summarize the latest science on lutein's role in the eye and the brain across different ages.

Indexed as

braincarotenoidscognitioneyelifespanluteinnutritionvisionzeaxanthin

Identifiers

PMID31321376
PMCPMC6629295
OpenAlexW2948347517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.