Evidence map›Paper›PMID 31321332›Full record

ArticleCurrent medical mycology2019

Cellular apoptosis: An alternative mechanism of action for caspofungin against

Parisa Aryamloo, Hossein Asgarian-Omran, Narges Aslani, Hadi Hossein-Nataj, Tahereh Shokohi, Hamid Badali, Mojtaba Nabili, Atefeh Abdollahi Gohar, Maryam Moazeni

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In one paragraph

Article in Current medical mycology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Parisa AryamlooStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Hossein Asgarian-OmranDepartment of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Narges AslaniInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hadi Hossein-NatajDepartment of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Tahereh ShokohiInvasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Hamid BadaliInvasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Mojtaba NabiliDepartment of Medical Laboratory Sciences, Sari Branch, Islamic Azad University, Sari, Iran.
Atefeh Abdollahi GoharStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Maryam MoazeniInvasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Mazandaran University of Medical Sciences · IRIslamic Azad University Sari Branch · IRTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAlthough the mechanism of action for echinocandins is known, the physiological mechanisms by which these antifungal agents cause cell death via the classical apoptotic pathways are not well-defined yet. Regarding this, the present study aimed to evaluate the mechanisms of caspofungin-induced MATERIALS AND

methodsFor the purpose of the study, the minimum inhibitory concentration (MIC) of caspofungin against

resultsAccording to the obtained MIC value (0.5 µg/mL),

conclusionAs the findings of the present study indicated, caspofungin promoted both necrosis and apoptosis of

Indexed as

Candida glabrataCaspofunginFlow cytometryMCA1NUC1

Identifiers

PMID31321332
PMCPMC6626714
OpenAlexW2962382878

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.