Evidence map›Paper›PMID 31321288›Full record

ArticleInternational journal of cardiology. Heart & vasculature2019

Incidence and predictors of left ventricular thrombus formation following acute ST-segment elevation myocardial infarction: A serial cardiac MRI study.

Justin Phan, Tuan Nguyen, John French, Daniel Moses, Glen Schlaphoff, Sidney Lo, Craig Juergens, Hany Dimitri, David Richards, Liza Thomas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Direct oral anticoagulants or warfarin in patients with left ventricular thrombus after ST-elevation myocardial infarction: a pilot trial and a prespecified meta-analysis of randomised trials.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
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  14. Mending the broken valentine heart: a case report.European heart journal. Case reports · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Justin PhanDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
Tuan NguyenDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
John FrenchDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
Daniel MosesSouth Western Sydney Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.
Glen SchlaphoffSouth Western Sydney Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.
Sidney LoDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
Craig JuergensDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
Hany DimitriDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
David RichardsDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
Liza ThomasDepartment of Cardiology, Liverpool Hospital, Sydney, New South Wales, Australia.
UNSW Sydney · AUSouth Western Sydney Local Health District · AULiverpool Hospital · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsLeft ventricular (LV) thrombus is a complication of acute ST-segment elevation myocardial infarction (STEMI). We determined the incidence and predictors of LV thrombus formation using serial cardiac magnetic resonance (CMR) and two-dimensional echocardiography studies. METHODS AND

resultsTwo hundred and ten patients underwent CMR (median 4 days [IQR 3-7]) and transthoracic echocardiography (median 4 days [IQR 3-7]) early after STEMI presentation with serial follow-up CMR (median 55 days [IQR 46-64]) and echocardiography studies (median 54 days [IQR 45-64]) performed subsequently. The incidence of LV thrombus was 12.3% (26/210) by CMR and 6.2% (13/210) by two-dimensional echocardiography. Echocardiography had 50% sensitivity and 100% specificity for LV thrombus detection compared to CMR. LV thrombus was found in 23.6% of patients with anterior STEMI (22/93). Ischaemic stroke occurred in 1.4% of patients (3/210). Patients with LV thrombus had lower baseline LV ejection fraction (LVEF) (34.9% vs 47.4%,

conclusionCMR increases the detection of LV thrombi which standard echocardiography may underestimate. Serial studies post-STEMI may improve detection of LV thrombus, which is more prevalent in patients with anterior infarction, moderate LV dysfunction and adverse LV remodelling. This subgroup of patients may represent a high-risk group for targeted serial screening with CMR.

Indexed as

Left ventricular thrombusMyocardial infarction

Identifiers

PMID31321288
PMCPMC6612928
OpenAlexW2956078656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.