Evidence map›Paper›PMID 31321238›Full record

ArticleBioMed research international2019

Is Prehospital Time Important for the Treatment of Severely Injured Patients? A Matched-Triplet Analysis of 13,851 Patients from the TraumaRegister DGU®.

Konstantin Klein, Rolf Lefering, Pascal Jungbluth, Sven Lendemans, Bjoern Hussmann

Abstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Impact of Delayed Trauma Unit Admission on Mortality and Disability in Traumatic Brain Injury Patients.International journal of environmental research and public health · 2025
    Observational
  4. Article
  5. The predictive value of serum lactate to forecast injury severity in trauma-patients increases taking age into account.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  6. Elevated serum lactate levels and age are associated with an increased risk for severe injury in trauma team activation due to trauma mechanism.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Konstantin KleinDepartment of Trauma and Hand Surgery, University Hospital, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), Witten/Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany.
Pascal JungbluthDepartment of Trauma and Hand Surgery, University Hospital, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Sven LendemansDepartment of Trauma Surgery, Alfried Krupp Hospital, Alfried-Krupp-Strasse 21, 45131 Essen, Germany.
Bjoern HussmannDepartment of Trauma Surgery, Alfried Krupp Hospital, Alfried-Krupp-Strasse 21, 45131 Essen, Germany.ORCID https://orcid.org/0000-0001-8333-6367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of time (the golden period of trauma) on the outcome of severely injured patients has been well known for a long time. While the duration of the prehospital phase has changed only slightly (average time: ~66 min) since the TraumaRegister DGU® (TR-DGU®) was implemented, mortality rates have decreased within the last 20 years. This study analyzed the influence of prehospital time on the outcome of trauma patients in a matched-triplet analysis. MATERIAL AND

methodsA total of 93,024 patients from the TraumaRegister DGU® were selected based on the following inclusion criteria: ISS ≥ 16, primary admission, age ≥ 16 years, and data were available for the following variables: prehospital intubation, blood pressure, mode of transportation, and age. The patients were assigned to one of three groups: group 1: 10-50 min (short emergency treatment time); group 2: 51-75 min (intermediate emergency treatment time); group 3: >75 min (long emergency treatment time). A matched-triplet analysis was conducted; matching was based on the following criteria: intubation at the accident site, rescue resources, Abbreviated Injury Scale (AIS) of the body regions, systolic blood pressure, year of the accident, and age.

resultsA total of 4,617 patients per group could be matched. The number of patients with a GCS score ≤8 was significantly higher in the first group (group 1: 36.6%, group 2: 33.5%, group 3: 30.3%; p < 0.001). Moreover, the number of patients who had to be resuscitated during the prehospital phase and/or upon arrival at the hospital was higher in group 1 (p = 0.010); these patients also had a significantly higher mortality (group 1: 20.4%, group 2: 18.1%, group 3: 15.9%; p ≤ 0.001). The number of measures performed during the prehospital phase (e.g., chest tube insertion) increased with treatment time.

conclusionsThe results suggest that survival after severe trauma is not only a matter of short rescue time but more a matter of well-used rescue time including performance of vital measures already in the prehospital setting. This also includes that rescue teams identify the severity of injuries more rapidly in the most-severely injured patients in critical condition than in less-severely injured patients and plan their interventions accordingly.

Indexed as

Time FactorsAdolescentAdultAgedEmergency Medical ServicesEmergency TreatmentFemaleGermanyHumansInjury Severity ScoreIntubationMaleMiddle AgedMultiple TraumaWounds and InjuriesYoung Adult

Identifiers

PMID31321238
PMCPMC6610751

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.