ArticleCentral Asian journal of global health2019
Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study.
Article in Central Asian journal of global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- Isolated Lateralized Overgrowth - Phenotypic Spectrum and Molecular Alterations.Indian journal of pediatrics · 2025Article
- Article
- A five-day-old child with lipid hemihypertrophy: A case report.Clinical case reports · 2024Article
- Overcoming Challenges in Hemihyperplasia Through Surgical Innovation and Genetic Diagnosis: A Case Report.Cureus · 2024Article
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Authors and funding
10 authors at 5 institutions in 4 countries.
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No grant is acknowledged in the PubMed record.
Abstract
introductionIsolated or congenital hemihypertrophy is a rare disorder characterized by asymmetric overgrowth of one side of the body. This article describes the protocol and preliminary results of a lateral body asymmetry (hemihypertrophy) screening procedure performed in healthy adolescents in a multicenter study. The reported incidence of hemihypertrophy varies between different publications and standardized protocols are needed to improve research in this area.
methodsOur screening program is taking place in Australia, Israel, Mexico, Ukraine and USA. Procedure includes two steps: (1) "three measurements - three questions" screening, or assessment of face, palms, and shins; (2) in-depth assessment of selected cases in order to exclude localized, lesional, and syndrome-related cases as well as body asymmetry within normative range and to select suspected cases of isolated hemihypertrophy. This step includes measurements of various anatomical regions and a detailed questionnaire.
resultsAt this stage, the screening procedure is completed and the selected participants are advised to refer to medical institutions for further clinical and genetic follow up to exclude possible tumors and other accompanying disorders.
conclusionWe present an easy-to-use selection tool to identify children with suspected IH, which results in the selection of the risk group that may benefit from referral to a pediatrician and a clinical geneticist.
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