Evidence map›Paper›PMID 31321152›Full record

ArticleCentral Asian journal of global health2019

Evaluation of micronuclei in oral mucosa of individuals exposed to ionizing radiation: a pilot study from Celaya, México.

Nicolas Padilla-Raygoza, María Del Rocio Adame Gutiérrez, Itza Zelene Moreno Martínez, Vicente Beltran-Campos, Silvia Del Carmen Delgado-Sandoval, Maria de Lourdes Garcia-Campos, Modesto Antonio Sosa-Aquino, Teodoro Cordova-Fraga, Rafael Guzman-Cabrera

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Central Asian journal of global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nicolas Padilla-RaygozaDepartment of Nursing and Obstetrics, Division of Health Sciences and Engineering, Universidad of Guanajuato Mutualismo, México.
María Del Rocio Adame GutiérrezAcademic Unity of Nursing N°1, University Autonomous of Guerrero, México.
Itza Zelene Moreno MartínezDivision of Health Sciences and Engineering, University of Guanajuato, México.
Vicente Beltran-CamposDepartment of Clinical Nursing, Division of Health Sciences and Engineering, University of Guanajuato, México.
Silvia Del Carmen Delgado-SandovalDepartment of Nursing and Obstetrics, Division of Health Sciences and Engineering, Universidad of Guanajuato Mutualismo, México.
Maria de Lourdes Garcia-CamposDepartment of Clinical Nursing, Division of Health Sciences and Engineering, University of Guanajuato, México.
Modesto Antonio Sosa-AquinoDepartment oh Physical Engineering, Division of Sciences and Engineering, University of Guanajuato, México.
Teodoro Cordova-FragaDepartment oh Physical Engineering, Division of Sciences and Engineering, University of Guanajuato, México.
Rafael Guzman-CabreraDepartmentof Electrical Engineering, Division of Engineerings, University of Guanajuato, México.
Universidad de Guanajuato · MXUniversidad Autónoma de Guerrero · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOccupational exposure to ionizing radiation can potentially lead to adverse health effects, including cancer and genetic defects. Genetic damage caused by radiation can be detected if micronuclei are observed. The objective of this pilot study was to detect the presence of micronuclei in cells of the oral mucosa in inidividuals occupationally exposed to ionizing radiation.

methodsWe implemented a pilot case-control study in which we compared oral mucosa micronuclei in 30 medical and nursing personnel in radiology centers in Celaya, Mexico, with 30 volunteers not exposed to ionizing radiation recruited from a public University. The oral mucosa was brushed and the amount of micronuclei was quantified. Chi-square test or t-test for two proportions were used to compared ionizing radiation and genetic damage between exposed and non-exposed groups.

resultsThe exposed group had an average of 5.37 ± 3.49 micronuclei and the non-exposed had 0.37 ± 0.61 (P<0.01). In the exposed group, 90% of participants exhibited genetic damage compared to 6.67% in the unexposed group (P<0.05).

conclusionIn this pilot study, medical and nursing staff from radiology centers presented with higher genetic damage compared to control group. Further studies are needed to identify the prevalence of genetic damage due to occupational radiation exposure in Mexico.

Indexed as

Genetic DamageIonizing RadiationMicronuclei

Identifiers

PMID31321152
PMCPMC6564099
OpenAlexW2943844764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.