Evidence map›Paper›PMID 31321058›Full record

Observational studyBMJ open respiratory research2019

Impact of blood group on survival following critical illness: a single-centre retrospective observational study.

Robert Slade, Raza Alikhan, Matt P Wise, Lam Germain, Simon Stanworth, Matt Morgan

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in BMJ open respiratory research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Is ABO blood type a risk factor for adjacent segment degeneration after lumbar spine fusion?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  3. Article
  4. Defining Current Patterns of Blood Product Use during Intensive Induction Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia Patients.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  5. Article
  6. Observational
  7. ABO blood types and sepsis mortality.Annals of intensive care · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert SladeAdult Critical Care, University Hospital of Wales, Cardiff and Vale University Healthcare NHS Trust, Cardiff, UK.
Raza AlikhanDepartment of Haematology, University Hospital of Wales, Cardiff and Vale University Healthcare NHS Trust, Cardiff, UK.
Matt P WiseAdult Critical Care, University Hospital of Wales, Cardiff and Vale University Healthcare NHS Trust, Cardiff, UK.
Lam GermainAdult Critical Care, University Hospital of Wales, Cardiff and Vale University Healthcare NHS Trust, Cardiff, UK.
Simon StanworthDepartement of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Matt MorganAdult Critical Care, University Hospital of Wales, Cardiff and Vale University Healthcare NHS Trust, Cardiff, UK.ORCID 0000-0002-2357-7190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Predicting patient outcomes following critical illness is challenging. Recent evidence has suggested that patients with blood group AB are more likely to survive following major cardiac surgery, and this is associated with a reduced number of blood transfusions. However, there are no current data to indicate whether a patient's blood group affects general intensive care outcomes. Objective: The objective of this study was to determine if ABO blood group affects survival in intensive care. The primary outcome measure was 90-day mortality with a secondary outcome measure of the percentage of patients receiving a blood transfusion. Design: Retrospective analysis of electronically collected intensive care data, blood group and transfusion data. Setting: General intensive care unit (ICU) of a major tertiary hospital with both medical and surgical patients. Patients: All patients admitted to ICU between 2006 and 2016 who had blood group data available. Intervention: None. Measurements and main results: 7340 patients were included in the study, blood group AB accounted for 3% (221), A 41% (3008), B 10.6% (775) and O 45.4% (3336). These values are similar to UK averages. Baseline characteristics between the groups were similar. Blood group AB had the greatest survival benefit (blood group AB 90-day survival estimate 76.75, 95% CI 72.89 to 80.61 with the overall estimate 72.07, 95% CI 71.31 to 72.82) (log-rank χ Conclusion: Although this is primarily a hypothesis generating study, intensive care patients with blood group AB appeared to have a higher 90-day survival compared with other blood groups. There was no correlation between blood group and percentage of patients receiving transfusion.

Indexed as

ABO Blood-Group SystemAdultAgedBlood TransfusionCritical CareCritical IllnessFemaleHospital MortalityHumansIntensive Care UnitsKaplan-Meier EstimateLength of StayMaleMiddle AgedPrognosisRetrospective StudiesABO Blood-Group Systemblood groupICUsurvival benefit

Identifiers

PMID31321058
PMCPMC6606056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.