Evidence map›Paper›PMID 31320992›Full record

ArticleOncotarget2019

Photodynamic therapy of cervical cancer by eradication of cervical cancer cells and cervical cancer stem cells.

Elvin Peter Chizenga, Rahul Chandran, Heidi Abrahamse

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  9. Cytotoxic Effects of Combinative ZnPcSInternational journal of molecular sciences · 2023
    Article
  10. Review
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  12. Article
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  15. Article
  16. Article
  17. Review
  18. Controlled killing of human cervical cancer cells by combined action of blue light and C-doped TiOPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elvin Peter ChizengaLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.
Rahul ChandranLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.
University of Johannesburg · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heterogeneous nature of cancer puts cancer stem cells (CSCs) at the beating heart of the tumour. Because of their inherent characteristics of stemness, CSCs evade putative cancer therapies, resulting in treatment resistance or tumour recurrence after a seemingly successful treatment. To prevent treatment resistance and cancer recurrence, killing the beating heart of the tumour is of utmost importance. This study therefore, sought to determine the effect of Photodynamic Therapy (PDT) in eradicating cervical cancer and cervical CSCs. Cervical CSCs were isolated from a cervical adenocarcinoma cell line, HeLa cells, and grown in liquid medium incubated at 37° C, 5% CO

Indexed as

cancer resistancecancer stem cellscervical cancerphotodynamic therapyphotosensitizer

Identifiers

PMID31320992
PMCPMC6633885
OpenAlexW2968681930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.