ReviewOxidative medicine and cellular longevity2019
Stay Fit, Stay Young: Mitochondria in Movement: The Role of Exercise in the New Mitochondrial Paradigm.
Review in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Effects of Mitoquinone (MitoQ) Supplementation on Aerobic Exercise Performance and Oxidative Damage: A Systematic Review and Meta-analysis.Sports medicine - open · 2024Pooled it
- Heart rate recovery as a marker of post-exercise lipid metabolism following moderate- and vigorous-intensity exercise.European journal of applied physiology · 2026Article
- Muscle movement and metabolism: exercise and skeletal muscle as mediators of health-a report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.The American journal of clinical nutrition · 2026Article
- Melatonin and mitochondrial protection in cardiac ischemia-reperfusion injury: mechanisms, evidence and translational perspectives.Basic research in cardiology · 2026Review
- Short-duration electrical pulse stimulation induces myokines and mitochondrial adaptations in C2C12 myotubes.Journal of muscle research and cell motility · 2026Article
- Effects of endurance training on skeletal muscle mitochondrial respiration in Siberian huskies and Alaskan huskies.Physiological reports · 2026Article
- Exercise interventions remodel the aging microenvironment to improve prognosis in older patients with cancer.Frontiers in immunology · 2026Review
- MyoQuant: An optimized image analysis algorithm for quantitative analysis of skeletal muscle fibers.MethodsX · 2025Article
- Mitochondrial adaptations from heat acclimation - A narrative review.Journal of thermal biology · 2025Review
- Impact of Body Composition on Peak Oxygen Uptake After Cardiac Rehabilitation.medRxiv : the preprint server for health sciences · 2025Article
- The Impact of Endurance Exercise on Routine Laboratory Parameters in Young Trained Individuals.Journal of clinical medicine · 2025Article
- The effectiveness of a high-intensity interval exercise on cardiometabolic health and quality of life in older adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Polarized or threshold training: is there a superior training intensity distribution to improve V̇OJournal of physiology and biochemistry · 2025Article
- Effects of Regular Habitual Exercise on Platelet Energetics in Male Recreational Contact Sports Student-Athletes: A Cross-Sectional Study.Health science reports · 2025Article
- Article
- Mitochondrial Dysfunction in Cardiac Disease: The Fort Fell.Biomolecules · 2024Review
- Review
- Mitochondrial Dysfunction and Risk Factors for Noncommunicable Diseases: From Basic Concepts to Future Prospective.Diseases (Basel, Switzerland) · 2024Review
- Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal muscles require the proper production and distribution of energy to sustain their work. To ensure this requirement is met, mitochondria form large networks within skeletal muscle cells, and during exercise, they can enhance their functions. In the present review, we discuss recent findings on exercise-induced mitochondrial adaptations. We emphasize the importance of mitochondrial biogenesis, morphological changes, and increases in respiratory supercomplex formation as mechanisms triggered by exercise that may increase the function of skeletal muscles. Finally, we highlight the possible effects of nutraceutical compounds on mitochondrial performance during exercise and outline the use of exercise as a therapeutic tool in noncommunicable disease prevention. The resulting picture shows that the modulation of mitochondrial activity by exercise is not only fundamental for physical performance but also a key point for whole-organism well-being.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.