Evidence map›Paper›PMID 31320871›Full record

ArticleCase reports in oncology

Lung Cancer Presenting as Skin Metastasis of the Back and Hand: A Case Series and Literature Review.

Misbahuddin Khaja, Daniel Mundt, Rizwan Ahmed Dudekula, Umair Ashraf, Shehriyar Mehershahi, Masooma Niazi, Dimitry Lvovsky, Sandeep Malik, Gilda Diaz-Fuentes

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Carcinoma lung with cutaneous metastasis: experience from an Indian institute.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cutaneous Metastases from Lung Adenocarcinoma.Case reports in dermatological medicine · 2020
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Misbahuddin KhajaDivision of Pulmonary and Critical Care Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Daniel MundtDepartment of Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Rizwan Ahmed DudekulaDivision of Pulmonary and Critical Care Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Umair AshrafDivision of Pulmonary and Critical Care Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Shehriyar MehershahiDepartment of Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Masooma NiaziDivision of Pathology, Bronx Lebanon Hospital Center Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Dimitry LvovskyDivision of Pulmonary and Critical Care Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Sandeep MalikDivision of Hematology and Oncology, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Gilda Diaz-FuentesDivision of Pulmonary and Critical Care Medicine, Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, New York, USA.
Mount Sinai Health System · USBronx-Lebanon Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer has the highest mortality of all cancers in the United States. The incidence of lung cancer with metastases to the skin varies between 1-12%, with the highest incidence seen in men. Here, we present two cases of lung cancer presenting as skin metastasis. The first patient was an 80-year-old African American male who presented to the hospital for evaluation of a right upper back mass. A few months prior to admission, he was found to have a left lung mass on CT scan of the chest, he underwent biopsy which showed poorly differentiated SCC of the lung. He also had a skin biopsy which showed poorly differentiated carcinoma in the dermis consistent with metastatic SCC. He was started on chemotherapy, but could not tolerate it. He was accepted to hospice. The second patient was a 78-year-old Hispanic female who presented to the hospital with dyspnea, and a dry cough. Upon physical examination, a 2 × 2 cm ulcerated, wart-like nodule on the right palm was noted. Subsequent CT scan of the chest showed a partial collapse of the right middle lobe. A biopsy of the hand mass revealed well-to-moderately differentiated metastatic SCC favoring lung origin. A bronchoscopy biopsy showed invasive SCC. Subsequently her condition worsened and she passed away. Metastasis to the skin is an unusual presenting symptom of lung cancer. It is therefore essential to consider metastasis as a diagnosis in a patient with both a skin lesion and a smoking history.

Indexed as

Metastatic skin lesionNon small cell lung cancerSquamous cell lung cancer

Identifiers

PMID31320871
PMCPMC6616052
OpenAlexW2953426524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.