ArticleScientific reports2019
Metabolic signatures of germination triggered by kinetin in Medicago truncatula.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Role of cytokinins in seed development in pulses and oilseed crops: Current status and future perspective.Frontiers in genetics · 2022Pooled it
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- Exploring the role of DNA damage response in seed priming to uncover key players for multi-stress tolerance.Journal of experimental botany · 2026Review
- PcMYBs responded to 6-BA to regulate PcCKXs to promote germination of primary rhizome buds of Polygonatum cyrtonema Hua.BMC plant biology · 2025Article
- Impact of cryopreservation on DNA damage in Acer platanoides L. seeds evaluated by the comet assay.Scientific reports · 2025Article
- Review
- Exploring seed characteristics and performance through advanced physico-chemical techniques.Scientific reports · 2024Article
- Potassium indole-3-butyric acid affects rice's adaptability to salt stress by regulating carbon metabolism, transcription factor genes expression, and biosynthesis of secondary metabolites.Frontiers in plant science · 2024Article
- Molecular dynamics of seed priming at the crossroads between basic and applied research.Plant cell reports · 2023Review
- Changes inFrontiers in plant science · 2023Article
- Experimental Evidence for Seed Metabolic Allometry in Barrel Medic (International journal of molecular sciences · 2022Article
- Salicylic Acid in Root Growth and Development.International journal of molecular sciences · 2022Review
- Oxidative damage and DNA repair in desiccated recalcitrant embryonic axes of Acer pseudoplatanus L.BMC plant biology · 2022Article
- Cryopreservation and low-temperature storage of seeds of3 Biotech · 2021Article
- Exploring microRNA Signatures of DNA Damage Response Using an Innovative System of Genotoxic Stress inFrontiers in plant science · 2021Article
- Hydropriming and Biopriming ImproveGenes · 2020Article
- A Snapshot of the Trehalose Pathway During Seed Imbibition inFrontiers in plant science · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present work, non-targeted metabolomics was used to investigate the seed response to kinetin, a phytohormone with potential roles in seed germination, still poorly explored. The aim of this study was to elucidate the metabolic signatures of germination triggered by kinetin and explore changes in metabolome to identify novel vigor/stress hallmarks in Medicago truncatula. Exposure to 0.5 mM kinetin accelerated seed germination but impaired seedling growth. Metabolite composition was investigated in seeds imbibed with water or with 0.5 mM kinetin collected at 2 h and 8 h of imbibition, and at the radicle protrusion stage. According to Principal Component Analysis, inositol pentakisphosphate, agmatine, digalactosylglycerol, inositol hexakisphosphate, and oleoylcholine were the metabolites that mostly contributed to the separation between 2 h, 8 h and radicle protrusion stage, irrespective of the treatment applied. Overall, only 27 metabolites showed significant changes in mean relative contents triggered by kinetin, exclusively at the radicle protrusion stage. The observed metabolite depletion might associate with faster germination or regarded as a stress signature. Results from alkaline comet assay, highlighting the occurrence of DNA damage at this stage of germination, are consistent with the hypothesis that prolonged exposure to kinetin induces stress conditions leading to genotoxic injury.
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