Evidence map›Paper›PMID 31320474›Full record

ArticleThe Journal of biological chemistry2019

Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast.

Suzanne J Admiraal, Daniel E Eyler, Michael R Baldwin, Emily M Brines, Christopher T Lohans, Christopher J Schofield, Patrick J O'Brien

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Pulmonary Inflammation and KRAS Mutation in Lung Cancer.Advances in experimental medicine and biology · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Suzanne J AdmiraalDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.ORCID 0000-0003-3334-2499
Daniel E EylerDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.
Michael R BaldwinDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.
Emily M BrinesDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.
Christopher T LohansDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, United Kingdom.
Christopher J SchofieldDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, United Kingdom.ORCID 0000-0002-0290-6565
Patrick J O'BrienDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600 pjobrien@umich.edu.ORCID 0000-0001-7853-8626
University of Michigan · USUniversity of Oxford · GB

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alexey I Nesvizhskii · 1988 to 2026
$178.2M
Cancer Research UKNCI NIH HHS P30 CA046592Wellcome Trust
6 · The paper itself

Abstract

The Mag1 and Tpa1 proteins from budding yeast (

Indexed as

Alkylating AgentsAlkylationCarrier ProteinsDealkylationDNA DamageDNA, FungalDNA GlycosylasesDNA RepairEndodeoxyribonucleasesEscherichia coliMethyl MethanesulfonateMutagensMutationOxidative StressSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAlkylating AgentsCarrier ProteinsDNA, FungalDNA GlycosylasesEndodeoxyribonucleasesMAG1 protein, S cerevisiaeMethyl MethanesulfonateMutagensSaccharomyces cerevisiae ProteinsTpa1 protein, S cerevisiaeAlkAAlkBbase excision repair (BER)DNA damageDNA repairhydroxylaseMag1oxidative dealkylationSaccharomyces cerevisiaeTpa1translation regulation

Identifiers

PMID31320474
PMCPMC6746446
OpenAlexW2963701626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.