ArticleJournal of the American Society of Nephrology : JASN2019
Higher eGFR at Dialysis Initiation Is Not Associated with a Survival Benefit in Children.
Article in Journal of the American Society of Nephrology : JASN, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Trends in chronic dialysis practices and outcomes in North American children: a 30-year NAPRTCS registry analysis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Association between estimated time with low glomerular filtration rate and access to transplant among youth with advanced chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2026Article
- Trends in Timing of Preemptive Kidney Transplantation and Association with Allograft and Survival Outcomes in Children.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Release of apoptosis inhibitor of macrophage (AIM) from pentameric IgM in serum predicts prognosis after hemodialysis initiation.Communications medicine · 2025Article
- Timing and Modality of Kidney Replacement Therapy in Children and Adolescents.Kidney international reports · 2024Article
- Incremental dialysis: review of the literature with pediatric perspective.Pediatric nephrology (Berlin, Germany) · 2024Review
- Epidemiology of pediatric chronic kidney disease/kidney failure: learning from registries and cohort studies.Pediatric nephrology (Berlin, Germany) · 2022Review
- Preexisting comorbidities are associated with the mortality rate as well as the predialysis adverse events in incident dialysis patients.Kidney research and clinical practice · 2021Article
- Early initiation of PD therapy in elderly patients is associated with increased risk of death.Clinical kidney journal · 2021Article
- Should we abandon GFR in the decision to initiate chronic dialysis?Pediatric nephrology (Berlin, Germany) · 2020Review
- Think Twice before Postponing Chronic Dialysis in Children.Journal of the American Society of Nephrology : JASN · 2019Article
- Authors' Reply.Journal of the American Society of Nephrology : JASN · 2019Article
- Time's Up! Start Dialysis Later in Children.Journal of the American Society of Nephrology : JASN · 2019Article
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundStudy findings suggest that initiating dialysis at a higher eGFR level in adults with ESRD does not improve survival. It is less clear whether starting dialysis at a higher eGFR is associated with a survival benefit in children with CKD.
methodsTo investigate this issue, we performed a retrospective cohort study of pediatric patients aged 1-18 years who, according to the US Renal Data System, started dialysis between 1995 and 2015. The primary predictor was eGFR at the time of dialysis initiation, categorized as higher (eGFR>10 ml/min per 1.73 m
resultsOf 15,170 children, 4327 (29%) had a higher eGFR (median eGFR, 12.8 ml/min per 1.73 m
conclusionsIn children with ESRD, a higher eGFR at dialysis initiation is associated with lower survival, particularly among children whose initial treatment modality is hemodialysis.
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