Evidence map›Paper›PMID 31320408›Full record

ArticleGenetics2019

Mutations in the S-Adenosylmethionine Synthetase Genes

Kellyn M Hoffert, Kathryn S P Higginbotham, Justin T Gibson, Stuart Oehrle, Erin D Strome

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kellyn M HoffertDepartment of Biological Sciences, Northern Kentucky University, Highland Heights, Kentucky 41099.ORCID 0000-0002-0191-458X
Kathryn S P HigginbothamDepartment of Biological Sciences, Northern Kentucky University, Highland Heights, Kentucky 41099.
Justin T GibsonDepartment of Biological Sciences, Northern Kentucky University, Highland Heights, Kentucky 41099.ORCID 0000-0003-2967-5338
Stuart OehrleWaters Field Laboratory, Chemistry Department, Northern Kentucky University, Highland Heights, Kentucky 41099.
Erin D StromeDepartment of Biological Sciences, Northern Kentucky University, Highland Heights, Kentucky 41099 stromee1@nku.edu.ORCID 0000-0002-6334-9619
Northern Kentucky University · US

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
Training Program in Cell, Molecular, and Developmental BiologyT32GM008111 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YODER, BRADLEY K. · 1985 to 2022
$5.4M
Investigation of Candidate Modifier Loci for Cancer SusceptibilityR15GM109269 · NIGMS · NORTHERN KENTUCKY UNIVERSITY · PI STROME, ERIN D · 2015 to 2015
$327k
NIGMS NIH HHS P20 GM103436NIGMS NIH HHS R15 GM109269NIGMS NIH HHS T32 GM008111
6 · The paper itself

Abstract

Maintenance of genome integrity is a crucial cellular focus that involves a wide variety of proteins functioning in multiple processes. Defects in many different pathways can result in genome instability, a hallmark of cancer. Utilizing a diploid

Indexed as

Genomic InstabilityGenome, FungalMethionine AdenosyltransferaseMutationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsS-AdenosylmethionineMethionine AdenosyltransferaseSaccharomyces cerevisiae ProteinsS-Adenosylmethioninecancer biologygenomic instabilitySaccharomyces cerevisiaeS-adenosylmethionine (AdoMet)yeast genetics

Identifiers

PMID31320408
PMCPMC6727793
OpenAlexW2964276475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.