Evidence map›Paper›PMID 31320374›Full record

ArticleBMJ case reports2019

Seizures, renal failure and acute respiratory failure: not your typical case of Henoch-Schonlein purpura.

Subhasish Bose, Samata Pathireddy, Krishna M Baradhi, Narothama Reddy Aeddula

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Subhasish BoseDepartment of Nephrology, Lynchburg Nephrology, Lynchburg, Virginia, USA.
Samata PathireddyDepartment of Internal Medicine, Deaconess Health System, Evansville, Indiana, USA.
Krishna M BaradhiDepartment of Nephrology, University of Oklahoma School of Community Medicine, Tulsa, Oklahoma, USA.
Narothama Reddy AeddulaDepartment of Medicine, Deaconess Health System, Evansville, Indiana, USA.
Deaconess Hospital · USIndiana University School of MedicineUniversity of Lynchburg · USUniversity of Oklahoma · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 30-year-old Caucasian woman with no prior medical history presented with pedal oedema, arthralgias and abdominal pain with diarrhoea, following a respiratory infection. She had mild abdominal tenderness along with a purpuric rash on the extremities and was anaemic. Following initial workup for anaemia and rash, her condition deteriorated with renal impairment, respiratory failure and seizures necessitating ventilatory support, dialysis and steroids. Serologies were negative, and skin biopsy showed leucocytoclastic vasculitis without vascular IgA deposition, and renal biopsy showed subendothelial, mesangial deposits of IgA with C3 indicative of Henoch-Schonlein purpura (HSP). She was treated with steroids, haemodialysis and on 6-month follow-up recovered renal function. We present the case to illustrate that HSP, though rare in adults, can present with multiorgan failure, with renal, pulmonary and central nervous system involvement, and the need for early diagnosis and prompt treatment for rapid clinical recovery.

Indexed as

Acute Kidney InjuryAdrenal Cortex HormonesAdultAnticonvulsantsBiopsyElectroencephalographyFemaleGlomerulonephritisHumansIgA VasculitisMagnetic Resonance ImagingRenal DialysisRespiration, ArtificialRespiratory Distress SyndromeSeizuresAdrenal Cortex HormonesAnticonvulsantsacute renal failureadult intensive careGI bleedinghaematology (incl blood transfusion)mechanical ventilation

Identifiers

PMID31320374
PMCPMC6663222
OpenAlexW2962867478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.