Evidence map›Paper›PMID 31320326›Full record

ArticleDevelopment (Cambridge, England)2019

FGF signaling patterns cell fate at the interface between tendon and bone.

Ryan R Roberts, Lauren Bobzin, Camilla S Teng, Deepanwita Pal, Creighton T Tuzon, Ronen Schweitzer, Amy E Merrill

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Interfacial Tissue Regeneration with Bone.Current osteoporosis reports · 2024
    Review
  6. Article
  7. Article
  8. Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  9. Article
  10. Targeted deletion of Fgf9 in tendon disrupts mineralization of the developing enthesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. The impact of Drew Noden's work on our understanding of craniofacial musculoskeletal integration.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Review
  15. Article
  16. Review
  17. Growth and mechanobiology of the tendon-bone enthesis.Seminars in cell & developmental biology · 2022
    Review
  18. Comparison of Tendon Development Versus Tendon Healing and Regeneration.Frontiers in cell and developmental biology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ryan R RobertsCenter for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA.
Lauren BobzinCenter for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA.
Camilla S TengDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Deepanwita PalResearch Division, Shriners Hospital for Children, Oregon Health & Science University, Portland, OR 97239, USA.
Creighton T TuzonCenter for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA.
Ronen SchweitzerResearch Division, Shriners Hospital for Children, Oregon Health & Science University, Portland, OR 97239, USA.
Amy E MerrillCenter for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA amerrill@usc.edu.ORCID 0000-0002-3660-1575
University of Southern California · USOregon Health & Science University · US

Funding

DOCTORAL AND POST-DOCTORAL TRAINING IN CRANIOFACIAL BIOLOGYT90DE021982 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PAINE, MICHAEL LANSDELL · 2011 to 2025
$6.2M
THE ROLE OF FGFR2 IN PROTEIN SYNTHESIS DURING SKELETAL DEVELOPMENTR01DE025222 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MERRILL, AMY E · 2015 to 2024
$3.7M
NIDCR NIH HHS R01 DE025222NIDCR NIH HHS T90 DE021982
6 · The paper itself

Abstract

Tendon and bone are attached by a transitional connective tissue that is morphologically graded from tendinous to osseous and develops from bipotent progenitors that co-express scleraxis (Scx) and Sox9 (Scx

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsBone and BonesCell DifferentiationChondrocytesFibroblast Growth FactorsGene Expression Regulation, DevelopmentalJawMiceMice, KnockoutReceptor, Fibroblast Growth Factor, Type 2Signal TransductionSOX9 Transcription FactorStem CellsTendonsTenocytesBasic Helix-Loop-Helix ProteinsFgfr2 protein, mouseFibroblast Growth FactorsReceptor, Fibroblast Growth Factor, Type 2Scx protein, mouseSox9 protein, mouseSOX9 Transcription FactorCraniofacial developmentEnthesisFGFMouseNotchPerichondriumTendon

Identifiers

PMID31320326
PMCPMC6703712
OpenAlexW2961752405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.