Evidence map›Paper›PMID 31320123›Full record

ArticleAtencion primaria

[Management of hyperglycaemia with non-insulin drugs in adult patients with type 2 diabetes].

Fernando Álvarez-Guisasola, Domingo Orozco-Beltrán, Ana M Cebrián-Cuenca, Manuel Antonio Ruiz Quintero, Escarlata Angullo Martínez, Luis Ávila Lachica, Carlos Ortega Millán, Elena Caride Miana, Jorge Navarro-Pérez, Julio Sagredo Perez and 2 more

Abstract read
In one paragraph

Article in Atencion primaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fernando Álvarez-GuisasolaMedicina Familiar y Comunitaria, Centro de Salud Ribera del Órbigo, Benavides de Órbigo, León, España.
Domingo Orozco-BeltránMedicina Familiar y Comunitaria, Unidad Investigación, Centro de Salud Cabo Huertas, Dpto. San Juan de Alicante, Alicante, España.
Ana M Cebrián-CuencaMedicina Familiar y Comunitaria, Centro de Salud Cartagena Casco, Cartagena, Murcia, España. Electronic address: anicebrian@gmail.com.
Manuel Antonio Ruiz QuinteroMedicina Familiar y Comunitaria, Centro de Salud Agost, Agost, Alicante, España.
Escarlata Angullo MartínezMedicina Familiar y Comunitaria, Centro de Salud Escola Graduada, Palma de Mallorca, España.
Luis Ávila LachicaMedicina Familiar y Comunitaria, UGC Vélez Norte, consultorio de Almáchar, Almáchar, Málaga, España.
Carlos Ortega MillánMedicina Familiar y Comunitaria, Centro de Salud de Pozoblanco, Pozoblanco, Córdoba, España.
Elena Caride MianaMedicina Familiar y Comunitaria, Centro de Salud Foietes, Benidorm, Alicante, España.
Jorge Navarro-PérezMedicina Familiar y Comunitaria, Hospital Clínico Universitario de Valencia, INCLIVA, Universitat de València, CIBERESP, Valencia, España.
Julio Sagredo PerezMedicina Familiar y Comunitaria, Centro de Salud Parque Europa, Pinto, Madrid, España.
Joan Barrot de la PuenteMedicina Familiar y Comunitaria, Centro de Salud Jordi Nadal, Salt, Girona, España.
Francesc Xavier Cos ClaramuntMedicina Familiar y Comunitaria, Universitat Autònoma de Barcelona, Barcelona, España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of diabetes mellitus type2 (DM2) includes healthy eating and exercise (150minutes/week) as basic pillars. For pharmacological treatment, metformin is the initial drug except contraindication or intolerance; in case of poor control, 8 therapeutic families are available (6 oral and 2 injectable) as possible combinations. An algorithm and some recommendations for the treatment of DM2 are presented. In secondary cardiovascular prevention, it is recommended to associate an inhibitor of the sodium-glucose cotransporter type 2 (iSGLT2) or a glucagon-like peptide-1 receptor agonist (arGLP1) in patients with obesity. In primary prevention if the patient is obese or overweight metformin should be combined with iSGLT2, arGLP1, or inhibitors of type4 dipeptidylpeptidase (iDPP4). If the patient does not present obesity, iDPP4, iSGLT2 or gliclazide, sulfonylurea, recommended due to its lower tendency to hypoglycaemia, may be used.

Indexed as

AlgorithmsDiabetes Mellitus, Type 2Dipeptidyl-Peptidase IV InhibitorsDrug Therapy, CombinationHumansHyperglycemiaHypoglycemic AgentsMetforminObesitySodium-Glucose Transporter 2Sodium-Glucose Transporter 2 InhibitorsDipeptidyl-Peptidase IV InhibitorsHypoglycemic AgentsMetforminSLC5A2 protein, humanSodium-Glucose Transporter 2Sodium-Glucose Transporter 2 InhibitorsAntidiabetic drugsDiabetes tipo 2Fármacos antidiabéticosHiperglucemiaHyperglycemiaType 2 diabetes

Identifiers

PMID31320123
PMCPMC6836897

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.