Evidence map›Paper›PMID 31319899›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2019

Evaluation of Peroxides and Chlorine Oxides as Disinfectants for Chemical Sterilization of Gnotobiotic Rodent Isolators.

LaTisha V Moody, Yukiko Miyamoto, Jonathan Ang, Philip J Richter, Lars Eckmann

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Loss of sialic acid side-chainProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Sterility testing of germ-free mouse colonies.Frontiers in immunology · 2023
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

LaTisha V MoodyAnimal Care Program, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California.
Yukiko MiyamotoDepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, California.
Jonathan AngDepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, California.
Philip J RichterAnimal Care Program, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California.
Lars EckmannDepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, California;, Email: leckmann@ucsd.edu.
University of California, San Diego · US

Funding

San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2019 to 2026
$10.8M
UCSD Postdoctoral Training Program in Laboratory Animal MedicineR25OD016569 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RICHTER, PHIL J · 2013 to 2017
$527k
NIDDK NIH HHS P30 DK120515NIH HHS R25 OD016569
6 · The paper itself

Abstract

Gnotobiotic animal research has expanded markedly over the past decade. Although germ-free animals were first described more than 100 y ago, little evidence-based guidance is available on best operational procedures. A key aspect of gnotobiotic technology is the sterilization of animal enclosures, most commonly flexible vinyl film isolators. The objective of this study was to determine the most effective methods for chemical sterilization of gnotobiotic isolators and associated equipment. As test microbes, we used bacteria from 4 different accidental isolator contaminations that occurred in a gnotobiotic core facility. Identification by 16S ribotyping revealed facultative anaerobic firmicutes, including several

Indexed as

Germ-Free LifeRodentiaAnimalsChlorine CompoundsDisinfectantsDisinfectionHousing, AnimalLaboratory Animal SciencePeroxidesSterilizationChlorine CompoundschlorosylDisinfectantsPeroxides

Identifiers

PMID31319899
PMCPMC6774453
OpenAlexW2964129847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.