Evidence map›Paper›PMID 31319627›Full record

ReviewNutrients2019

The Sex-Gender Effects in the Road to Tailored Botanicals.

Ilaria Campesi, Annalisa Romani, Flavia Franconi

Abstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ilaria CampesiDipartimento di Scienze Biomediche, Università degli Studi di Sassari, 07100 Sassari, Italy. icampesi@uniss.it.
Annalisa RomaniLaboratorio PHYTOLAB (Pharmaceutical, Cosmetic, Food supplement Technology and Analysis)-DiSIA Università degli Studi di Firenze, 50019 Firenze, Italy. annalisa.romani@unifi.it.
Flavia FranconiLaboratory of Sex-gender Medicine, National Institute of Biostructures and Biosystems, 07100 Sassari, Italy.

Funding

Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro "Bando BRIC 2016"
6 · The paper itself

Abstract

Phenols are a wide family of phytochemicals that are characterized by large chemical diversity and are considered to bioactive molecules of foods, beverages, and botanicals. Although they have a multitude of biological actions, their beneficial effects are rarely evidenced in clinical practice. This may occur due to the presence of numerous confounders, such as the modulation of phenol bioavailability, which can be regulated by microbiota, age, sex-gender. Sex-gender is an important determinant of health and well-being, and has an impact on environmental and occupational risks, access to health care, disease prevalence, and treatment outcomes. In addition, xenobiotic responses may be strongly influenced by sex-gender. This review describes how sex-gender differentially influences the activities of phenols also in some critical periods of women life such as pregnancy and lactation, considering also the sex of fetuses and infants. Thus, sex-gender is a variable that must be carefully considered and should be used to propose directions for future research on the road to tailored medicine and nutrition.

Indexed as

FemaleHumansMalePhytochemicalsSex FactorsPhytochemicalsdevelopmental trajectorylactationmicrobiotapharmacokineticsphenolspregnancysex–gender

Identifiers

PMID31319627
PMCPMC6682902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.