ArticleViruses2019
Long-Term Circulation of Atypical Porcine Pestivirus (APPV) within Switzerland.
Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Characterization of Pestivirus scrofae infection in the tissues of a persistently infected boar.Porcine health management · 2026Article
- Transmission Dynamics of Gilts Persistently Infected with Atypical Porcine Pestivirus.Viruses · 2026Article
- Detection and genetic characterization of atypical porcine pestivirus in wild boars in European Russia.Frontiers in microbiology · 2026Article
- First detection and genetic characterization of atypical Porcine pestivirus in pigs, Thailand.Scientific reports · 2025Article
- Prevalence estimation of Pestivirus scrofae (atypical porcine pestivirus) among Hungarian pig herds and the effects of different sample types on detection rates.Porcine health management · 2025Article
- Isolation and Phylogenetic Analysis of Atypical Porcine Pestivirus Isolates Identified in Russian Swine Herds.Viruses · 2024Article
- The Pestivirus RNase EViruses · 2024Article
- Article
- Screening for atypical porcine pestivirus in Swedish boar semen used for artificial insemination and a characterisation of the seminal RNA microbiome including the virome.BMC veterinary research · 2023Article
- Development of a Crystal Digital RT-PCR for the Detection of Atypical Porcine Pestivirus.Veterinary sciences · 2023Article
- A Review on Pathological and Diagnostic Aspects of Emerging Viruses-Veterinary sciences · 2022Review
- DNAJC14-Independent Replication of the Atypical Porcine Pestivirus.Journal of virology · 2022Article
- Detection and localization of atypical porcine pestivirus in the testicles of naturally infected, congenital tremor affected piglets.Transboundary and emerging diseases · 2022Article
- Frequent Occurrence of Simultaneous Infection with Multiple Rotaviruses in Swiss Pigs.Viruses · 2022Article
- New Emergence of the Novel Pestivirus Linda Virus in a Pig Farm in Carinthia, Austria.Viruses · 2022Article
- Genetic diversity and detection of atypical porcine pestivirus infections.Journal of animal science · 2022Article
- Genetic Diversity of Hepatitis E Virus Type 3 in Switzerland-From Stable to Table.Animals : an open access journal from MDPI · 2021Article
- Screening of Swiss Pig Herds for Hepatitis E Virus: A Pilot Study.Animals : an open access journal from MDPI · 2021Article
- Article
- Evolution and genetic diversity of atypical porcine pestivirus (APPV) from piglets with congenital tremor in Guangxi Province, Southern China.Veterinary medicine and science · 2021Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2015, a new pestivirus was described in pig sera in the United States. This new "atypical porcine pestivirus" (APPV) was later associated with congenital tremor (CT) in newborn piglets. The virus appears to be distributed worldwide, but the limited knowledge of virus diversity and the use of various diagnostic tests prevent direct comparisons. Therefore, we developed an APPV-specific real-time RT-PCR assay in the 5'UTR of the viral genome to investigate both retro- and prospectively the strains present in Switzerland and their prevalence in domestic pigs. Overall, 1080 sera obtained between 1986 and 2018 were analyzed, revealing a virus prevalence of approximately 13% in pigs for slaughter, whereas it was less than 1% in breeding pigs. In the prospective study, APPV was also detected in piglets displaying CT. None of the samples could detect the Linda virus, which is another new pestivirus recently reported in Austria. Sequencing and phylogenetic analysis revealed a broad diversity of APP viruses in Switzerland that are considerably distinct from sequences reported from other isolates in Europe and overseas. This study indicates that APPV has already been widely circulating in Switzerland for many years, mainly in young animals, with 1986 being the earliest report of APPV worldwide.
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