Evidence map›Paper›PMID 31319551›Full record

ArticleBiosensors2019

Diazonium-Modified Screen-Printed Electrodes for Immunosensing Growth Hormone in Blood Samples.

Nan Li, Ari M Chow, Hashwin V S Ganesh, Melanie Ratnam, Ian R Brown, Kagan Kerman

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nan LiDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada.
Ari M ChowDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada.
Hashwin V S GaneshDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada.
Melanie RatnamCentre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada.
Ian R BrownCentre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada.
Kagan KermanDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada. kagan.kerman@utoronto.ca.ORCID 0000-0003-3511-8570
University of Toronto · CA

Funding

Canada Foundation for Innovation 35272Canada Research Chairs 950-231116Natural Sciences and Engineering Research Council of Canada 3655Ontario Ministry of Research, Innovation and Science 35272
6 · The paper itself

Abstract

Altered growth hormone (GH) levels represent a major global health challenge that would benefit from advances in screening methods that are rapid and low cost. Here, we present a miniaturized immunosensor using disposable screen-printed carbon electrodes (SPCEs) for the detection of GH with high sensitivity. The diazonium-based linker layer was electrochemically deposited onto SPCE surfaces, and subsequently activated using covalent agents to immobilize monoclonal anti-GH antibodies as the sensing layer. The surface modifications were monitored using contact angle measurements and X-ray photoelectron spectroscopy (XPS). The dissociation constant, K

Indexed as

Biosensing TechniquesElectrodesImmunoassayAnimalsDiazonium CompoundsElectrochemical TechniquesEnzyme-Linked Immunosorbent AssayGrowth HormoneRatsSensitivity and SpecificitySpectrum AnalysisSurface Plasmon ResonanceDiazonium CompoundsGrowth Hormonediazonium graftingelectrochemical impedance spectroscopygrowth hormoneimmunosensorreal samples

Identifiers

PMID31319551
PMCPMC6784379
OpenAlexW2961677907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.