Evidence map›Paper›PMID 31319476›Full record

ReviewInternational journal of molecular sciences2019

Endoplasmic Reticulum Export of GPI-Anchored Proteins.

Sergio Lopez, Sofia Rodriguez-Gallardo, Susana Sabido-Bozo, Manuel Muñiz

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Role ofBiomedical reports · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Frontiers in microbiology · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. To the Surface and Back: Exo- and Endocytic Pathways inFrontiers in cell and developmental biology · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sergio LopezDepartment of Cell Biology, University of Seville, 41012 Seville, Spain.
Sofia Rodriguez-GallardoDepartment of Cell Biology, University of Seville, 41012 Seville, Spain.
Susana Sabido-BozoDepartment of Cell Biology, University of Seville, 41012 Seville, Spain.
Manuel MuñizDepartment of Cell Biology, University of Seville, 41012 Seville, Spain. mmuniz@us.es.ORCID 0000-0001-8011-6991

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España BFU2017-89700-P
6 · The paper itself

Abstract

Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory cargo to the Golgi apparatus. The COPII machinery must adapt to the existing wide variety of different types of cargo proteins and to different cellular needs for cargo secretion. The study of the ER export of glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs), a special glycolipid-linked class of cell surface proteins, is contributing to address these key issues. Due to their special biophysical properties, GPI-APs use a specialized COPII machinery to be exported from the ER and their processing and maturation has been recently shown to actively regulate COPII function. In this review, we discuss the regulatory mechanisms by which GPI-APs are assembled and selectively exported from the ER.

Indexed as

AnimalsCOP-Coated VesiclesEndoplasmic ReticulumGolgi ApparatusHumansMembrane ProteinsOligosaccharidesProtein Transport(6-O-aminoethylphosphonato-mannopyranosyl)-(1-2)-mannopyranosyl-(1-6)-mannopyranosyl-(1-4)-(2-amino-2-deoxyglucopyranosyl)-(1-6)-1-O-(1,2-di-O-octadecanoyl-sn-glyceryl-phosphonato)-myo-inositolMembrane ProteinsOligosaccharidesCOPII coatendoplasmic reticulumGPI-anchored proteinp24 complex

Identifiers

PMID31319476
PMCPMC6678536

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.