Evidence map›Paper›PMID 31319171›Full record

ArticleAnnals of vascular surgery2019

Length Redundancy and Twist Improve the Biomechanical Properties of Polytetrafluoroethylene Bypass Grafts.

Regent Lee, Miranda Stoddart, Igor Dyson, Ismail Cassimjee, Ashok Handa, Christopher P Cheng

Abstract read
In one paragraph

Article in Annals of vascular surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Regent LeeNuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, Oxfordshire, UK. Electronic address: regent.lee@nds.ox.ac.uk.
Miranda StoddartNuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, Oxfordshire, UK.
Igor DysonDepartment of Engineering Science, University of Oxford, Oxford, Oxfordshire, UK.
Ismail CassimjeeNuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, Oxfordshire, UK.
Ashok HandaNuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, Oxfordshire, UK.
Christopher P ChengNuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, Oxfordshire, UK; Department of Vascular Surgery, Stanford University, Palo Alto, CA. Electronic address: cpc@stanford.edu.

Funding

Medical Research Council MC_PC_16082
6 · The paper itself

Abstract

backgroundThe iliofemoropopliteal artery significantly changes path length during normal hip and knee flexion. Prosthetic bypass grafts, such as polytetrafluoroethylene (PTFE) grafts, are relatively stiff and thus can subject graft anastomoses to high tension when the path length increases. The aim of this study was to examine the influence of length redundancy and twist on the biomechanical properties of PTFE bypass grafts.

methodsUnreinforced and ring-reinforced PTFE grafts were loaded in an axial mechanical testing machine to measure the tensile and compressive axial forces with varying levels of length redundancy and axial twist.

resultsAdding 5-15% length redundancy to a graft decreases the force to cause 5% extension by > 90% without substantially increasing shortening forces. Adding 4.5°/cm of axial twist imparts a corkscrew shape to the graft without increasing extension or shortening forces in the presence of length redundancy. Ring-reinforced PTFE grafts require more length redundancy to experience these reductions in forces especially in the presence of axial twist.

conclusionsA modest amount of length redundancy and twist (i.e., a cork-screw condition) confers improved biomechanical properties in a PTFE graft, especially in ring-reinforced grafts. This should be taken into consideration when fashioning an arterial bypass graft in the iliofemoropopliteal segment.

Indexed as

Blood Vessel ProsthesisHemodynamicsProsthesis DesignBiomechanical PhenomenaBlood Vessel Prosthesis ImplantationCompressive StrengthElasticityLower ExtremityMaterials TestingPolytetrafluoroethyleneProsthesis FailureStress, MechanicalTensile StrengthPolytetrafluoroethylene

Identifiers

PMID31319171
PMCPMC6900574

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.