Evidence map›Paper›PMID 31318962›Full record

SynthesisPloS one2019

The diagnostic performance of PET/CT scans for the detection of para-aortic metastatic lymph nodes in patients with cervical cancer: A meta-analysis.

Weiying Yu, Changgui Kou, Wei Bai, Xiao Yu, Ruixin Duan, Bo Zhu, Yuanyuan Li, Wanqing Hua, Xiaojun Ren, Yanming Yang

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. PET-CT radiomics and artificial intelligence for predicting lymph node metastasis in cervical cancer: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Curative treatment for stage IIIC2 cervical cancer: what to expect?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  7. False negative rate atBMC cancer · 2021
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Weiying YuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Changgui KouDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Wei BaiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Xiao YuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Ruixin DuanDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Bo ZhuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Yuanyuan LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Wanqing HuaDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Xiaojun RenDepartment of Radiotherapy, Second Hospital of Jilin University, Changchun, Jilin, China.
Yanming YangDepartment of Radiotherapy, Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0003-0614-7882
Jilin University · CNSecond Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe performed a meta-analysis to evaluate the diagnostic value of positron emission tomography/computed tomography (PET/CT) in the detection of para-aortic lymph node metastasis in cervical cancer.

methodsWe searched the PubMed, Embase, Web of Science, Cochrane Library, Chinese Biological Medicine (CBM), Chinese National Knowledge Infrastructure (CNKI), Wanfang and VIP databases in all languages from their inception to September 2018. Stat15.0 software was used to obtain pooled estimates of sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), and negative likelihood ratio (NLR) as well as a summary receiver operating characteristic (SROC) curves. Deek's funnel plot was used to assess publication bias. QUADAS-2 was used to evaluate the quality of the studies. The protocol for this meta-analysis is registered in PROSPERO (CRD42019115330).

resultsWe obtained 14 studies, and the pooled estimates for sensitivity and specificity of PET/CT were 0.71 (95% confidence interval (CI) = 0.54-0.83) and 0.97 (95% CI = 0.93-0.98), respectively. Pooled PLR and NLR were 21.53 and 0.30, respectively. The diagnostic odds ratio (DOR) was70.59, and the area under the curve (AUC) was 0.95.

conclusionPET/CT is an effective and important imaging method for the diagnosis of para-aortic lymph node metastasis in early cervical cancer.

Indexed as

Positron Emission Tomography Computed TomographyFemaleHumansLymphatic MetastasisLymph NodesOdds RatioPositron-Emission TomographyPublication BiasROC CurveUterine Cervical Neoplasms

Identifiers

PMID31318962
PMCPMC6638976
OpenAlexW2962003705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.