Evidence map›Paper›PMID 31318629›Full record

ArticlePsychological science2019

Inheritance of Neural Substrates for Motivation and Pleasure.

Zhi Li, Yi Wang, Chao Yan, Eric F C Cheung, Anna R Docherty, Pak C Sham, Raquel E Gur, Ruben C Gur, Raymond C K Chan

Abstract read
In one paragraph

Article in Psychological science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Understanding Anhedonia from a Genomic Perspective.Current topics in behavioral neurosciences · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhi Li1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.
Yi Wang1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.
Chao Yan3 Key Laboratory of Brain Functional Genomics, School of Psychology and Cognitive Science, East China Normal University.
Eric F C Cheung4 Castle Peak Hospital, Hong Kong, China.
Anna R Docherty5 Department of Psychiatry, University of Utah School of Medicine.
Pak C Sham7 Centre for Genomic Sciences, The University of Hong Kong.
Raquel E Gur10 Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Ruben C Gur10 Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Raymond C K Chan1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.ORCID 0000-0002-3414-450X

Funding

Modeling Dimensionality and Genetic Heterogeneity in SchizophreniaK01MH109765 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI DOCHERTY, ANNA R. · 2016 to 2019
$675k
NIMH NIH HHS K01 MH109765
6 · The paper itself

Abstract

Despite advances in the understanding of the reward system and the role of dopamine in recent decades, the heritability of the underlying neural mechanisms is not known. In the present study, we examined the hemodynamic activation of the nucleus accumbens (NAcc), a key hub of the reward system, in 86 healthy monozygotic twins and 88 healthy dizygotic twins during a monetary-incentive-delay task. The participants also completed self-report measures of pleasure. Using voxelwise heritability mapping, we found that activation of the bilateral NAcc during the anticipation of monetary gains had significant heritability (

Indexed as

AdolescentAlgorithmsAnticipation, PsychologicalBrain MappingCuesDopamineGenetic VariationHumansMagnetic Resonance ImagingMotivationNucleus AccumbensPhenotypePleasureQuantitative Trait, HeritableRewardTwins, DizygoticDopamineheritabilitymotivationnucleus accumbenspleasurereward system

Identifiers

PMID31318629
PMCPMC6794661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.