ReviewAccounts of chemical research2019
Hydrogen Bond Enhanced Halogen Bonds: A Synergistic Interaction in Chemistry and Biochemistry.
Review in Accounts of chemical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 166 citations in OpenAlex.
- Use of Halogenated Units for the Construction of Artificial Carbohydrate Receptors.Molecules (Basel, Switzerland) · 2026Article
- Unveiled Impact ofACS physical chemistry Au · 2026Article
- Design of a halogen bond catalyzed DNA endonuclease.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Studies About the Effect of Halogenated Solvents on the Fluorescence Properties of 9-Aryl-Substituted Isoquinolinium Derivatives - A Case Study.Journal of fluorescence · 2025Article
- Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition.Nature chemistry · 2025Article
- Unprecedented carbonic anhydrase inhibition mechanism: Targeting histidine 64 side chain through a halogen bond.Archiv der Pharmazie · 2025Article
- Illuminating the Performance of Electron Withdrawing Groups in Halogen Bonding.Chemphyschem : a European journal of chemical physics and physical chemistry · 2024Article
- Unraveling the Strength and Nature of Se∙∙∙O Chalcogen Bonds: A Comparative Study of SeFMolecules (Basel, Switzerland) · 2024Article
- Light-Up Fluorescence and Circularly Polarized Luminescence in Achiral Interlocked Framework via Adaptive Lone Pair-π Interaction Confinement.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- In Situ X-Ray Techniques Unraveling Charge Distribution Induced by Halogen Bonds in Solvates of an Iodo-Substituted Squaraine Dye.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Chalcogen-Bond-Assisted Formation of the N→C Dative Bonds in the Complexes between Chalcogenadiazoles/Chalcogenatriazoles and Fullerene CMolecules (Basel, Switzerland) · 2024Article
- Benzoyl Valine Quasiracemates: Pairing CFCrystal growth & design · 2024Article
- Article
- Combination of Hydrogen and Halogen Bonds in the Crystal Structures of 5-Halogeno-1Molecules (Basel, Switzerland) · 2024Article
- A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder.Nucleic acids research · 2023Article
- Halogen bonding-driven chiral amplification of a bimetallic gold-copper cluster through hierarchical assembly.Science advances · 2023Article
- Halogen Bond-Involving Self-Assembly of Iodonium Carboxylates: Adding a Dimension to Supramolecular Architecture.International journal of molecular sciences · 2023Article
- The interplay between hydrogen and halogen bonding: substituent effects and their role in the hydrogen bond enhanced halogen bond.Chemical science · 2023Article
- The Realm of Unconventional Noncovalent Interactions in Proteins: Their Significance in Structure and Function.ACS omega · 2023Review
- Halogen bonds, chalcogen bonds, pnictogen bonds, tetrel bonds and other σ-hole interactions: a snapshot of current progress.Acta crystallographica. Section C, Structural chemistry · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The halogen bond (XB) has become an important tool for molecular design in all areas of chemistry, including crystal and materials engineering and medicinal chemistry. Its similarity to the hydrogen bond (HB) makes the relationship between these interactions complex, at times competing against and other times orthogonal to each other. Recently, our two laboratories have independently reported and characterized a synergistic relationship, in which the XB is enhanced through direct intramolecular HBing to the electron-rich belt of the halogen. In one study, intramolecular HBing from an amine polarizes the iodopyridinium XB donors of a bidentate anion receptor. The resulting HB enhanced XB (or HBeXB) preorganizes and further augments the XB donors. Consequently, the affinity of the receptor for halogen anions was significantly increased. In a parallel study, a
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.