Evidence map›Paper›PMID 31318312›Full record

ArticleMolecular biology of the cell2019

Key within-membrane residues and precursor dosage impact the allotopic expression of yeast subunit II of cytochrome

Diana Rubalcava-Gracia, Juan García-Rincón, Ruy Pérez-Montfort, Patrice Paul Hamel, Diego González-Halphen

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Diana Rubalcava-GraciaInstituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Juan García-RincónInstituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Ruy Pérez-MontfortInstituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Patrice Paul HamelDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210.
Diego González-HalphenInstituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Universidad Nacional Autónoma de México · MXThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimentally relocating mitochondrial genes to the nucleus for functional expression (allotopic expression) is a challenging process. The high hydrophobicity of mitochondria-encoded proteins seems to be one of the main factors preventing this allotopic expression. We focused on subunit II of cytochrome

Indexed as

Cell NucleusCytosolElectron Transport Complex IVGene Expression Regulation, FungalGenes, MitochondrialMembrane ProteinsMitochondriaMitochondrial Membrane Transport ProteinsMitochondrial ProteinsProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteinscytochrome C oxidase subunit IIElectron Transport Complex IVMembrane ProteinsMitochondrial Membrane Transport ProteinsMitochondrial ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID31318312
PMCPMC6741066
OpenAlexW2962744518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.