Evidence map›Paper›PMID 31317770›Full record

Observational studyCancer control : journal of the Moffitt Cancer Center

Modified Folfox6 as Adjuvant Chemotherapy in Vietnamese Patients With Colorectal Cancer.

T Quang Nguyen, T Oanh Bui, P Thao Tran, V Thuan Tran, V Hieu Nguyen, Q Hoan Chu, T A Tuyet Bui, N Quynh Le, V Quang Le, V Tu Dao

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05494320 (The Effect of ATP-Binding Cassette C2), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05494320 unknown statusnot on this map

The Effect of ATP-Binding Cassette C2 (ABCC2) Transporter Genetic Polymorphism on Neurotoxicity in Gastrointestinal Cancer Patients Receiving Oxaliplatin -Based Chemotherapy

TypeobservationalSponsorAin Shams UniversityRan2021 to 2022Enrolled120ConditionsGastrointestinal CancerArmsFolfox Protocol
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Scientific Evidence for Cancer Control in Vietnam.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

T Quang Nguyen1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
T Oanh Bui1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
P Thao Tran1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
V Thuan Tran1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
V Hieu Nguyen1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
Q Hoan Chu1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
T A Tuyet Bui1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
N Quynh Le1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
V Quang Le1 Vietnam National Cancer Hospital, Hanoi, Vietnam.
V Tu Dao1 Vietnam National Cancer Hospital, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is the third most common cancer and the second leading cause of death from cancer worldwide. In Vietnam, the disease is the fifth leading cancer (8.9%), with 14 733 new cases in 2018. In recent years, the mFolfox6 regimen has been indicated commonly as the adjuvant chemotherapy after curative resection for patients with colorectal cancer. However, the efficacy of the regimen in Vietnamese patients has not been assessed and reported. In this retrospective study, we reviewed medical records of 83 patients with stage II or stage III colorectal cancer who received mFOLFOX6 regimen in order to investigate simultaneously survival and safety of this chemotherapy regimen. Three-year overall and disease-free survival were 84.3% and 79.5%, respectively. Our data revealed that postoperative Carcinoma Embryonic Antigen (CEA) level was a significant prognostic factor for survival, with hazard ratio of 3.83 and 3.67, respectively (

Indexed as

AdolescentAdultAgedAntineoplastic Combined Chemotherapy ProtocolsCarcinoembryonic AntigenChemotherapy, AdjuvantColectomyColorectal NeoplasmsDisease-Free SurvivalFemaleFluorouracilHumansLeucovorinMaleMiddle AgedNeoplasm StagingCarcinoembryonic AntigenFluorouracilLeucovorinOrganoplatinum Compoundsadjuvant chemotherapycolorectal cancermFOLFOX 6 regimeoverall survival

Identifiers

PMID31317770
PMCPMC6640065

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.