ArticleJournal of veterinary internal medicine2019
Clinical and laboratory findings and survival time associated with cardiac cachexia in dogs with congestive heart failure.
Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 28 citations in OpenAlex.
- Muscle Mass Is a Better Predictor of Survival in Dogs With Chronic Kidney Disease Compared to Body Condition Score.Journal of animal physiology and animal nutrition · 2026Article
- Dietary management of normoalbuminaemic canine chronic enteropathies.The Journal of small animal practice · 2026Review
- Rare stability in dogs with myxomatous mitral valve disease: Clinical observations of loop diuretic withdrawal after congestive heart failure.Open veterinary journal · 2026Article
- Prognostic utility of red blood cell distribution width-based ratios and their individual components for mortality prediction in dogs with acute pancreatitis.Frontiers in veterinary science · 2026Article
- Cardiac Chemodectoma With Recurrent Pericardial Effusion and Cardiac Tamponade in an Alaskan Malamute: A Case Report.Case reports in veterinary medicine · 2026Article
- CT-based optimization of hindlimb muscle measurement levels and development of a hindlimb muscle condition score in dogs.Frontiers in veterinary science · 2026Article
- Monoplane Simpson's Method Is Reliable for Left Atrial Volume Assessment in Small Dogs with Myxomatous Mitral Valve Disease.Veterinary sciences · 2025Article
- Serum Concentrations of Insulin-like Growth Factor-1 (IGF-1), 26S Proteasome (26S PSM), and 3-Methylhistidine (3-MH) in Cats with Hypertrophic Cardiomyopathy.Animals : an open access journal from MDPI · 2025Article
- Dogs with advanced myxomatous mitral valve disease have evidence of gastrointestinal bacterial translocation and systemic inflammation.PloS one · 2025Article
- Alteration of clinical parameters before mortality and prognostic outcomes of pulmonary hypertension in dogs with myxomatous mitral valve disease.Open veterinary journal · 2024Article
- Self-Reported Utilization of International (ACVIM Consensus) Guidelines and the Latest Clinical Trial Results on the Treatment of Dogs with Various Stages of Myxomatous Mitral Valve Degeneration: A Survey among Veterinary Practitioners.Animals : an open access journal from MDPI · 2024Article
- Hypoglycemia after Mitral Valve Repair in Dogs.Veterinary sciences · 2024Article
- Self-Reported Utilization of International Guidelines for Staging Dogs with Myxomatous Mitral Valve Degeneration: A Survey among Veterinary Practitioners.Veterinary sciences · 2023Article
- Evidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure.Metabolomics : Official journal of the Metabolomic Society · 2022Article
- Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease.Journal of the American Heart Association · 2021Article
- Red Cell Distribution Width Has a Negative Prognostic Role in Dogs with Myxomatous Mitral Valve Disease.Animals : an open access journal from MDPI · 2021Article
- The gut microbiome in dogs with congestive heart failure: a pilot study.Scientific reports · 2020Article
- Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study.Journal of veterinary internal medicine · 2020Article
- Cardiac cachexia in cats with congestive heart failure: Prevalence and clinical, laboratory, and survival findings.Journal of veterinary internal medicine · 2020Article
- Clinical and laboratory findings and survival time associated with cardiac cachexia in dogs with congestive heart failure.Journal of veterinary internal medicine · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCardiac cachexia, loss of muscle mass associated with congestive heart failure (CHF), is associated with increased morbidity and shorter survival times in people, but an association between cardiac cachexia and survival has not been reported in dogs.
objectivesTo determine the prevalence of cachexia and its associations with clinical, laboratory, and survival data in dogs with CHF. ANIMALS: Two hundred sixty-nine dogs with CHF.
methodsRetrospective cohort study. Cachexia was defined by 1 of 2 definitions: (1) mild, moderate, or severe muscle loss or (2) weight loss of ≥5% in 12 months or less. Variables were compared between dogs with and without cachexia.
resultsOne hundred thirty of 269 dogs (48.3%) had cardiac cachexia based on muscle loss, whereas 67 of 159 dogs (42.1%) with pre-evaluation body weights had cachexia based on weight loss. Dogs with cachexia (based on muscle loss) were significantly older (P = .05), more likely to have a cardiac arrhythmia (P = .02), had higher chloride concentrations (P = .04), and had a lower body condition score (P < .001), hematocrit (P = .006), hemoglobin (P = .006), and albumin (P = .004) concentrations. On multivariable analysis, cachexia (P = .05), clinically important tachyarrhythmias (P < .001), azotemia (P < .001), and being under- or overweight (both P = .003) were associated with shorter survival times. CONCLUSIONS AND CLINICAL IMPORTANCE: Cardiac cachexia in common in dogs with CHF and is associated with significantly shorter survival. This emphasizes the importance of preventing, diagnosing, and treating muscle loss in dogs with CHF.
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