Evidence map›Paper›PMID 31317437›Full record

ArticleJournal of nephrology2019

Chronic kidney disease in preeclamptic patients: not found unless searched for-Is a nephrology evaluation useful after an episode of preeclampsia?

Zineb Filali Khattabi, Marilisa Biolcati, Antioco Fois, Antoine Chatrenet, Delphine Laroche, Rossella Attini, Marie Therese Cheve, Giorgina Barbara Piccoli

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Adding creatinine to routine pregnancy tests: a decision tree for calculating the cost of identifying patients with CKD in pregnancy.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  5. The Ethanolic Extract ofPharmaceutics · 2022
    Article
  6. Review
  7. Pre-eclampsia is a valuable opportunity to diagnose chronic kidney disease: a multicentre study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Zineb Filali KhattabiCentre Hospitalier Le Mans, Avenue Roubillard 196, 7200, Le Mans, France.
Marilisa BiolcatiDipartimento di Chirurgia, University of Torino, Turin, Italy.
Antioco FoisCentre Hospitalier Le Mans, Avenue Roubillard 196, 7200, Le Mans, France.
Antoine ChatrenetCentre Hospitalier Le Mans, Avenue Roubillard 196, 7200, Le Mans, France.
Delphine LarocheCentre Hospitalier Le Mans, Avenue Roubillard 196, 7200, Le Mans, France.
Rossella AttiniDipartimento di Chirurgia, University of Torino, Turin, Italy.
Marie Therese CheveCentre Hospitalier Le Mans, Avenue Roubillard 196, 7200, Le Mans, France.
Giorgina Barbara PiccoliCentre Hospitalier Le Mans, Avenue Roubillard 196, 7200, Le Mans, France. gbpiccoli@yahoo.it.ORCID http://orcid.org/0000-0002-2632-4009
Centre Hospitalier du Mans · FRUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreeclampsia (PE) and chronic kidney disease (CKD) are linked by an only partially known cause-effect relationship. Knowledge on prevalence of CKD in PE patients is needed for evaluating the diagnostic yield of nephrology work-up after PE.

methodsThe study was undertaken in the Centre Hospitalier Le Mans (CHM), setting of tertiary level obstetric service (about 3500 deliveries/year). PE was identified on hospital's discharge codes; after review, the study included 99 patients, 36 of which were also evaluated in Nephrology. A descriptive analysis was performed as appropriate. Logistic multiple regression tested the outcome "CKD diagnosis"; covariates that emerged as significant were selected; only singletons were included. Analysis was performed in SPSS. The ethics committee of the CHM approved the study.

resultsPrevalence of CKD was 14%; CKD was in stage 1 in 8/14 (57%); 5 patients were in stage 2 (36%), 1 in stage 3 (7%). CKD was known or acknowledged in 1 case only. Diagnoses included reflux nephropathy-other malformations (5 cases), kidney stones-chronic pyelonephritis (3), PKD (1), interstitial nephropathy (2), diabetic nephropathy (1), albuminuria in metabolic syndrome (2). At the logistic regression analysis, preterm delivery [OR 7.849 (1.667-36.968)] and a baby normal for gestational age [> 10th centile; OR 6.193 (1.400-27.394)] were significantly correlated with the diagnosis of CKD.

conclusionsWithin the limits of a single-center study, our data quantify CKD as common in PE women and suggest the presence of a "CKD phenotype" characterised by preterm delivery and adequate growth, implying that CKD is compatible with good placental function up to the last phase of pregnancy.

Indexed as

AdultFemaleFranceGestational AgeHumansIncidenceInfant, NewbornMaleNephrologyPre-EclampsiaPregnancyPremature BirthPrevalenceRenal Insufficiency, ChronicRisk AssessmentRisk FactorsChronic kidney diseaseHypertensive disorders of pregnancyObesityPreeclampsiaRisk factors

Identifiers

PMID31317437
OpenAlexW2957793208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.