ReviewInternational journal of legal medicine2019
Analysis of RNA in the estimation of post-mortem interval: a review of current evidence.
Review in International journal of legal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- microRNAs as New Biomolecular Markers to Estimate Time since Death: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Potential Role of mRNA in Estimating Postmortem Interval: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- The Role of DNA Degradation in the Estimation of Post-Mortem Interval: A Systematic Review of the Current Literature.International journal of molecular sciences · 2020Pooled it
- Evaluation of post-mortem interval based on gingival tissue hypoxia inducible factor-1α gene expression.The Journal of forensic odonto-stomatology · 2026Article
- Experimental study of mRNA from human dental pulp tissue for late postmortem interval estimation.Scientific reports · 2026Article
- Evaluation of RNA Stability and Molecular Biomarkers for Post-Mortem Interval Estimation in Rat Organs.International journal of molecular sciences · 2025Article
- Transcriptomic analysis at 48 h postmortem: a proof of concept for the identification of biomarkers to estimate time since death.Molecular biology reports · 2025Article
- Postmortem Changes in mRNA Expression and Tissue Morphology in Brain and Femoral Muscle Tissues of Rat.International journal of molecular sciences · 2025Article
- The Latest Advances in Omics Technology for Assessing Tissue Damage: Implications for the Study of Sudden Cardiac Death.International journal of molecular sciences · 2025Review
- Circular RNA circFat3 as a biomarker for construction of postmortem interval Estimation models in mouse brain tissues at multiple temperatures.Scientific reports · 2025Article
- Development of Mathematical Models Using circRNA Combinations (International journal of molecular sciences · 2025Article
- Dental DNA Mutations Occurring after Death: A Novel Method for Post-Mortem Interval (PMI) Estimation.International journal of molecular sciences · 2024Article
- RNA Analysis in Forensic Molecular Biology.Deutsches Arzteblatt international · 2024Review
- A computational approach to estimate postmortem interval using postmortem computed tomography of multiple tissues based on animal experiments.International journal of legal medicine · 2024Article
- Spitting in the wind?-The challenges of RNA sequencing for biomarker discovery from saliva.International journal of legal medicine · 2024Article
- Handheld hyperspectral imaging as a tool for the post-mortem interval estimation of human skeletal remains.Heliyon · 2024Article
- miR-26a/30d/152 are reliable reference genes for miRNA quantification in skin wound age estimation.Forensic sciences research · 2023Article
- Review
- Review of the current and potential use of biological and molecular methods for the estimation of the postmortem interval in animals and humans.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2023Review
- The smell of death. State-of-the-art and future research directions.Frontiers in microbiology · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-mortem interval (PMI) determination is one of the most important issues in forensic sciences. In the past, forensic scientists provided different approaches (physical, chemical, and entomological) for the estimation of PMI without success.However, advances in molecular biology over the last two decades have allowed us to assess the time-dependent degradation of biological markers (e.g., proteins, DNA, and RNA). Thus, the aim of the manuscript is to provide a review of the recent progress in the estimation of PMI using molecular biology methods, mainly focusing on the potential usefulness of RNA markers. To this end, 29 studies have been systematically reviewed, each one chosen according to specific inclusion/exclusion criteria. The selected studies evaluated the contribution of endogenous reference genes in different biological samples in order to determine the PMI based on post-mortem RNA degradation as a function of other influencing factors such as time, cause of death, and environmental conditions.
Indexed as
Identifiers
31317317What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.