Evidence map›Paper›PMID 31317219›Full record

ArticlePediatric cardiology2019

Ivabradine in Post-operative Junctional Ectopic Tachycardia (JET): Breaking New Ground.

Mani Ram Krishna, Mohammed Farooq Kunde, Raman Krishna Kumar, Seshadri Balaji

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. [Research progress in the application of ivabradine in children with cardiovascular diseases].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  5. Circulation. Arrhythmia and electrophysiology · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Ivabradine and endothelium: an update.Therapeutic advances in cardiovascular disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mani Ram KrishnaDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences, AIMS Ponekkara (P.O), Kochi, 682041, India. mann_comp@hotmail.com.
Mohammed Farooq KundeDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences, AIMS Ponekkara (P.O), Kochi, 682041, India.
Raman Krishna KumarDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences, AIMS Ponekkara (P.O), Kochi, 682041, India.
Seshadri BalajiDepartment of Pediatrics (Cardiology), Oregon Health & Science University, Portland, OR, USA.
Amrita Institute of Medical Sciences and Research Centre · INOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Junctional ectopic tachycardia (JET) is the commonest tachyarrhythmia in the early post-operative period in children undergoing open-heart surgery. It frequently leads to hemodynamic instability and needs to be managed aggressively. Amiodarone is the first-line agent along with non-pharmacological interventions. We report our initial experience with the use of Ivabradine in post-operative JET. A retrospective case records review of children with post-operative JET during the period from June 2018 to May 2019 was performed. Eight patients with post-operative JET were treated with Ivabradine during this period. The first patient was initially treated with Amiodarone. All eight patients responded to Ivabradine. The initial response was rate control permitting overdrive pacing. One patient had recurrence of JET 10 h after Ivabradine and after return to sinus rhythm. Amiodarone was administered along with the second dose of Ivabradine resulting in remission to sinus rhythm. Ivabradine appears to be an effective alternative to Amiodarone in children with post-operative JET based on our initial clinical experience.

Indexed as

Administration, IntranasalCardiac Surgical ProceduresCardiovascular AgentsChild, PreschoolFemaleHumansInfantIvabradineMalePostoperative ComplicationsRetrospective StudiesTachycardia, Ectopic JunctionalTreatment OutcomeCardiovascular AgentsIvabradineAnti-arrhythmic therapyFunny current channel (I f)Post-operative arrhythmias

Identifiers

PMID31317219
OpenAlexW2962451411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.