Evidence map›Paper›PMID 31317056›Full record

ArticleAmerican journal of clinical and experimental urology2019

Void sorcerer: an open source, open access framework for mouse uroflowmetry.

Zunyi Wang, Emmanuel Contreras Guzman, Amit Nimunkar, Kimberly P Keil, Chad M Vezina, William A Ricke, Jill Macoska, Dale E Bjorling

Open access · greenAbstract read
In one paragraph

Article in American journal of clinical and experimental urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Real-Time Void Spot Assay.Journal of visualized experiments : JoVE · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Micturition defects and altered bladder function in theAmerican journal of clinical and experimental urology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zunyi WangDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison Madison, WI, USA.
Emmanuel Contreras GuzmanDepartment of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison Madison, WI, USA.
Amit NimunkarDepartment of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison Madison, WI, USA.
Kimberly P KeilDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California-Davis Davis, CA, USA.
Chad M VezinaDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison Madison, WI, USA.
William A RickeDepartment of Urology, School of Medicine and Public Health, University of Wisconsin-Madison Madison, WI, USA.
Jill MacoskaCenter for Personalized Cancer Therapy, University of Massachusetts-Boston Boston, MA, USA.
Dale E BjorlingDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison Madison, WI, USA.
University of Wisconsin–Madison · USUniversity of California, Davis · USUniversity of Massachusetts Boston · US

Funding

Role of Beta-Catenin in Urinary DysfunctionU54DK104310 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI STRAND, DOUGLAS WILLIAM, VEZINA, CHAD M. · 2014 to 2023
$12.8M
PCB induced neurogenic inflammation mediates bladder dysfunctionK99ES029537 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI STIETZ, KIMBERLY PRESTON KEIL · 2018 to 2019
$191k
NIDDK NIH HHS U54 DK104310NIEHS NIH HHS K99 ES029537
6 · The paper itself

Abstract

Observational and experimental studies of rodent voiding behaviors have greatly contributed to our understanding of lower urinary tract function including the complex social, environmental, and internal stimuli that affect voiding in health and models of disease. Void spot assays (VSA), cystometry (awake or anesthetized), and uroflowmetry are techniques commonly used in rodent models to assess voiding. Uroflowmetry is non-invasive and can be performed multiple times in the same freely moving animals and can be used to generate synchronized video corresponding to each void to characterize micturition patterns (e.g., droplets versus solid stream). However, approaches to evaluate uroflowmetry in rodent models vary widely across laboratories. Most importantly, an open access software to run these tests is not freely available (although complete systems are commercially available), limiting use of this important assay. We developed the Void Sorcerer, an uroflowmetry system for mice for reliable determination of frequency, voided volume, voiding duration, interval times between micturitions, and flow rate. This report provides a detailed description of how to build this system and includes open access software for developing uroflowmetry capability in their laboratories and improve upon it in a cost-effective manner. Our goals are to improve access, increase reproducibility among laboratories, and facilitate standardizing testing procedures.

Indexed as

micturitionmouseopen access platformRaspberry Pi 3Uroflowetryvoiding

Identifiers

PMID31317056
PMCPMC6627548
OpenAlexW2981726609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.