ArticleFrontiers in veterinary science2019
Microbiota-Related Changes in Unconjugated Fecal Bile Acids Are Associated With Naturally Occurring, Insulin-Dependent Diabetes Mellitus in Dogs.
Article in Frontiers in veterinary science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 55 citations in OpenAlex.
- Shotgun Metagenomics Reveals Gut Microbiome Remodeling with Altered Taxonomic Composition and Functional Potential in Diabetic Dogs.Animals : an open access journal from MDPI · 2026Article
- The Collaborative Collapse: Bile Acid Dysmetabolism as a Central Pathogenic Driver in Canine and Feline Multi-Systemic Disorders-From Mechanisms to Precision Therapeutics.Veterinary sciences · 2026Review
- Glucose-Lowering Effects and Safety ofMicroorganisms · 2025Article
- The effect of lyophilised oral faecal microbial transplantation on functional outcomes in dogs with diabetes mellitus.The Journal of small animal practice · 2025Article
- Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025Review
- Gut microbiota diversity among humans, elephants, livestock and wild herbivores in Chitwan National Park bears implications for conservation medicine.Scientific reports · 2025Article
- Comparison of mucosal microbiota populations across the gastrointestinal tract of healthy dogs.Animal microbiome · 2025Article
- Oral microbiota in cesarean-delivered puppies.Frontiers in veterinary science · 2025Article
- Nutritional Factors Related to Canine Gallbladder Diseases-A Scoping Review.Veterinary sciences · 2024Review
- Decoding the Gut Microbiome in Companion Animals: Impacts and Innovations.Microorganisms · 2024Review
- Determination of Bile Acids in Canine Biological Samples: Diagnostic Significance.Metabolites · 2024Review
- Collaborative Metabolism: Gut Microbes Play a Key Role in Canine and Feline Bile Acid Metabolism.Veterinary sciences · 2024Review
- Flavonoids in mitigating the adverse effects of canine endotoxemia.Frontiers in veterinary science · 2024Article
- Characterization of the Gut Microbiome in Healthy Dogs and Dogs with Diabetes Mellitus.Animals : an open access journal from MDPI · 2023Article
- Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics.The Veterinary record · 2023Article
- Oligosaccharides and diet-related dilated cardiomyopathy in beagles.Frontiers in veterinary science · 2023Article
- Canine Fecal Microbiota Transplantation: Current Application and Possible Mechanisms.Veterinary sciences · 2022Review
- Domestic Environment and Gut Microbiota: Lessons from Pet Dogs.Microorganisms · 2022Review
- Analysis of the gut microbiome in dogs and cats.Veterinary clinical pathology · 2022Review
- Longitudinal analysis of the rectal microbiome in dogs with diabetes mellitus after initiation of insulin therapy.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus (DM) in humans has recently been associated with altered intestinal microbiota. The consequences of intestinal dysbiosis, such as increased intestinal permeability and altered microbial metabolites, are suspected to contribute to the host inflammatory state and peripheral insulin resistance. Human diabetics have been shown to have changes in bile acid (BA) metabolism which may be detrimental to glycemic control. The purpose of this study was to examine BA metabolism in dogs with naturally-occurring, insulin-dependent DM and to relate these findings to changes in the intestinal microbiota. A prospective observational study of adult dogs with a clinical diagnosis of DM (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.