ReviewJournal of exercise rehabilitation2019
Effect of nutrients and exhaustive exercise on brain function.
Review in Journal of exercise rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 13 citations in OpenAlex.
- Dietary Patterns, Serum BDNF and Fatty Acid Profiles in Physically Active Male Young Adults: A Cluster Analysis Study.Nutrients · 2024Article
- The Ketogenic Diet Improves Gut-Brain Axis in a Rat Model of Irritable Bowel Syndrome: Impact on 5-HT and BDNF Systems.International journal of molecular sciences · 2022Article
- Exercise and Organ Cross Talk.Advances in experimental medicine and biology · 2020Review
- BDNF levels in adolescent patients with anorexia nervosa increase continuously to supranormal levels 2.5 years after first hospitalization.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological evidence suggests that health-oriented eating habits are associated with maintaining optimal cognitive ability. Nutrients are functional bioactive molecules promoting human health and essential components as well. Docosahexaenoic acid (DHA; 22:6n-3), one of polyunsaturated fatty acids (PUFAs) is synthesized through elongation pathway from linolenic acid (81:3n-3) which is recognized as important source of brain function. Endurance physical exercise and energy restriction was also recognized of cardiovascular stress adjustment by enhancing brainstem cholinergic activity as well as brain function. However, we even do not know the exact neuronal mechanisms about the nutrients, β-hydroxybutyrate (β-HB) and myokine impacts on brain-derived neurotropic factor (BDNF) activation. Therefore, this review focuses on recent evidence that explains how nutrients and prolonged exercise can affect nervous system pathways that are associated with improving brain function. The results revealed that frequent consumption of polyphenols and n-3 PUFAs could modify gastrointestinal environment with beneficial microorganisms. It may suggest a new hypothesis that gastrointestinal microbiome could influence cognitive function in addition to the traditional etiological pathway. And moreover, prolonged physical exercise includes open skill sports which is induced by β-oxidation of free fatty acids stimulate BDNF. And also β-HB production which is induced by carbohydrate depletion, hypoglycemia, or fasting stimulate BDNF production that acts an significantly important roles in cognitive function and acting on brain function with brain metabolism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.